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    • Latest Articles
    • COVID-19 Research and News from ASM Journals
    • mSphere of Influence: Commentaries from Early Career Microbiologists
    • Archive
  • Topics
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superantigens

  • Open Access
    Staphylococcal Virulence Factors on the Skin of Atopic Dermatitis Patients
    Research Article | Host-Microbe Biology
    Staphylococcal Virulence Factors on the Skin of Atopic Dermatitis Patients

    For the first time, we show that secreted staphylococcal virulence factors can be quantified at the protein level directly from skin swabs obtained from the skin of atopic dermatitis patients. This technique eliminates the need to culture Staphylococcus aureus and then test the strain’s potential to produce secreted virulence factors. Our methodology shows that...

    Mary C. Moran, Michael P. Cahill, Matthew G. Brewer, Takeshi Yoshida, Sara Knowlden, Nelissa Perez-Nazario, Patrick M. Schlievert, Lisa A. Beck
  • Open Access
    Temporal and Racial Differences Associated with Atopic Dermatitis <span class="named-content genus-species" id="named-content-1">Staphylococcus aureus</span> and Encoded Virulence Factors
    Research Article | Host-Microbe Biology
    Temporal and Racial Differences Associated with Atopic Dermatitis Staphylococcus aureus and Encoded Virulence Factors

    Monitoring pathogen emergence provides insight into how pathogens adapt in the human population. Secreted virulence factors, important contributors to infections, may differ in a manner dependent on the strain and host. Temporal changes of Staphylococcus aureus toxigenic potential, for example, in encoding toxic shock syndrome toxin 1 (TSST-1), contributed to an...

    Joseph A. Merriman, Elizabeth A. Mueller, Michael P. Cahill, Lisa A. Beck, Amy S. Paller, Jon M. Hanifin, Peck Y. Ong, Lynda Schneider, Denise C. Babineau, Gloria David, Alexandre Lockhart, Keli Artis, Donald Y. M. Leung, Patrick M. Schlievert
  • Open Access
    Phenotypes and Virulence among <span class="named-content genus-species" id="named-content-1">Staphylococcus aureus</span> USA100, USA200, USA300, USA400, and USA600 Clonal Lineages
    Research Article | Host-Microbe Biology
    Phenotypes and Virulence among Staphylococcus aureus USA100, USA200, USA300, USA400, and USA600 Clonal Lineages

    S. aureus is the leading cause of infective endocarditis in the developed world, affecting ~40,000 individuals each year in the United States, and the second leading cause of bacteremia (D. R. Murdoch et al., Arch Intern Med 169:463–473, 2009, http://dx.doi.org/10.1001/archinternmed.2008.603 , and H....

    Jessica M. King, Katarina Kulhankova, Christopher S. Stach, Bao G. Vu, Wilmara Salgado-Pabón
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