protective antigen
- Opinion/Hypothesis | Therapeutics and PreventionQuestionable Efficacy of Therapeutic Antibodies in the Treatment of Anthrax
Inhalational anthrax caused by Bacillus anthracis, a spore-forming Gram-positive bacterium, is a highly lethal infection. Antibodies targeting the protective antigen (PA) binding component of the toxins have recently been authorized as an adjunct to antibiotics, although no conclusive evidence demonstrates that anthrax antitoxin therapy has any significant benefit. We...