plasmid shuttle vector
- Research Article | Host-Microbe BiologyDevelopment of a Plasmid Shuttle Vector System for Genetic Manipulation of Chlamydia psittaci
Psittacosis, caused by avian C. psittaci, has a major economic impact in the poultry industry worldwide and represents a significant risk for zoonotic transmission to humans. In the past decade, the tools of genetic manipulation have been improved for chlamydial molecular studies. While several genetic tools have been mainly developed in...
- Research Article | Host-Microbe BiologyThe Genetic Transformation of Chlamydia pneumoniae
The absence of tools for the genetic manipulation of C. pneumoniae has hampered research into all aspects of its biology. In this study, we established a novel reproducible method for C. pneumoniae transformation based on a plasmid shuttle vector system. We constructed a...