phlebovirus

  • Open Access
    Differential Antagonism of Human Innate Immune Responses by Tick-Borne <em>Phlebovirus</em> Nonstructural Proteins
    Research Article | Host-Microbe Biology
    Differential Antagonism of Human Innate Immune Responses by Tick-Borne Phlebovirus Nonstructural Proteins

    Since 2011, there has been a large expansion in the number of emerging tick-borne viruses that have been assigned to the Phlebovirus genus. Heartland virus (HRTV) and SFTS virus (SFTSV) were found to cause severe disease in humans, unlike other documented tick-borne phleboviruses such as Uukuniemi virus (UUKV). Phleboviruses encode nonstructural proteins (NSs) that enable them to counteract the human innate antiviral defenses....

    Veronica V. Rezelj, Ping Li, Vidyanath Chaudhary, Richard M. Elliott, Dong-Yan Jin, Benjamin Brennan
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