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  • Articles
    • Latest Articles
    • COVID-19 Research and News from ASM Journals
    • mSphere of Influence: Commentaries from Early Career Microbiologists
    • Archive
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microbiota

  • Open Access
    Monitoring COVID-19 Transmission Risks by Quantitative Real-Time PCR Tracing of Droplets in Hospital and Living Environments
    Research Article | Clinical Science and Epidemiology
    Monitoring COVID-19 Transmission Risks by Quantitative Real-Time PCR Tracing of Droplets in Hospital and Living Environments

    Several studies evaluated the presence of SARS-CoV-2 in the environment. Saliva and nasopharyngeal droplets can land on objects and surfaces, creating fomites.

    Andrea Piana, Maria Eugenia Colucci, Federica Valeriani, Adriano Marcolongo, Giovanni Sotgiu, Cesira Pasquarella, Lory Marika Margarucci, Andrea Petrucca, Gianluca Gianfranceschi, Sergio Babudieri, Pietro Vitali, Giuseppe D’Ermo, Assunta Bizzarro, Flavio De Maio, Matteo Vitali, Antonio Azara, Ferdinando Romano, Maurizio Simmaco, Vincenzo Romano Spica
  • Open Access
    Nasal Tissue Extraction Is Essential for Characterization of the Murine Upper Respiratory Tract Microbiota
    Research Article | Host-Microbe Biology
    Nasal Tissue Extraction Is Essential for Characterization of the Murine Upper Respiratory Tract Microbiota

    The nasal microbiota is composed of species that play a role in the colonization success of pathogens, including Streptococcus pneumoniae and Staphylococcus aureus. Murine models provide the ability to explore disease pathogenesis, but little is known about the natural murine nasal microbiota.

    ...
    L. Patrick Schenck, Joshua J. C. McGrath, Daphnée Lamarche, Martin R. Stämpfli, Dawn M. E. Bowdish, Michael G. Surette
  • Open Access
    The Initial Gut Microbiota and Response to Antibiotic Perturbation Influence <span class="named-content genus-species" id="named-content-1">Clostridioides difficile</span> Clearance in Mice
    Research Article | Host-Microbe Biology
    The Initial Gut Microbiota and Response to Antibiotic Perturbation Influence Clostridioides difficile Clearance in Mice

    Clostridioides difficile is a leading nosocomial infection. Although perturbation to the gut microbiota is an established risk, there is variation in who becomes asymptomatically colonized, develops an infection, or has adverse infection outcomes. Mouse models of C. difficile infection (CDI) are...

    Sarah Tomkovich, Joshua M. A. Stough, Lucas Bishop, Patrick D. Schloss
  • Open Access
    <span class="named-content genus-species" id="named-content-1">Dolosigranulum pigrum</span> Cooperation and Competition in Human Nasal Microbiota
    Research Article | Host-Microbe Biology
    Dolosigranulum pigrum Cooperation and Competition in Human Nasal Microbiota

    Staphylococcus aureus and Streptococcus pneumoniae infections cause significant morbidity and mortality in humans. For both, nasal colonization is a risk factor for infection. Studies of nasal microbiota identify Dolosigranulum pigrum...

    Silvio D. Brugger, Sara M. Eslami, Melinda M. Pettigrew, Isabel F. Escapa, Matthew T. Henke, Yong Kong, Katherine P. Lemon
  • Open Access
    Oxalate-Degrading <span class="named-content genus-species" id="named-content-1">Bacillus subtilis</span> Mitigates Urolithiasis in a <span class="named-content genus-species" id="named-content-2">Drosophila melanogaster</span> Model
    Research Article | Therapeutics and Prevention
    Oxalate-Degrading Bacillus subtilis Mitigates Urolithiasis in a Drosophila melanogaster Model

    Kidney stone disease is a morbid condition that is increasing in prevalence, with few nonsurgical treatment options. The majority of stones are composed of calcium oxalate. Unlike humans, some microbes can break down oxalate, suggesting that microbial therapeutics may provide a novel treatment for kidney stone patients. This study demonstrated that Bacillus subtilis...

    Kait F. Al, Brendan A. Daisley, Ryan M. Chanyi, Jennifer Bjazevic, Hassan Razvi, Gregor Reid, Jeremy P. Burton
  • Open Access
    Dilution as a Solution: Targeting Microbial Populations with a Simplified Dilution Strategy
    Commentary | Host-Microbe Biology
    Dilution as a Solution: Targeting Microbial Populations with a Simplified Dilution Strategy

    The gut microbiota is an integral part of maintaining resistance against infection by Clostridioides (Clostridium) difficile, a pathogen of increasing concern in both health care and community settings. The recent article by J. M. Auchtung, E. C. Preisner, J. Collins, A. I. Lerma, and R. A. Britton (mSphere 5:e00387-20, 2020, https://doi.org/10.1128/mSphere....

    Disha Bhattacharjee, Anna M. Seekatz
  • Open Access
    mSphere of Influence: Translating Gut Microbiome Studies To Benefit Human Health
    Commentary | Host-Microbe Biology
    mSphere of Influence: Translating Gut Microbiome Studies To Benefit Human Health

    Anna M. Seekatz works in the field of the gut microbiome as it related to infectious diseases. In this “mSphere of Influence” article, she reflects on how two studies, “The impact of a consortium of fermented milk strains on the gut microbiome of gnotobiotic mice and monozygotic twins” (N. P. McNulty, T. Yatsunenko, A. Hsiao, et al., Sci Transl Med 3:106ra106, 2011) and “High-throughput DNA sequence analysis reveals stable engraftment...

    Anna M. Seekatz
  • Open Access
    mSphere of Influence: the Mycobiota in Human Health and Disease
    Commentary | Host-Microbe Biology
    mSphere of Influence: the Mycobiota in Human Health and Disease

    Soo Chan Lee works in the field of medical mycology. In this mSphere of Influence article, he reflects on how “Interactions between commensal fungi and the C-type lectin receptor Dectin-1 influence colitis” (Science 336:1314–1317, 2012, https://doi.org/10.1126/science.1221789) by I. D. Iliev, V. A. Funari, K. D. Taylor, Q.

    Soo Chan Lee
  • Open Access
    mSphere of Influence: an Inupiat Journey in Science
    Commentary | Host-Microbe Biology
    mSphere of Influence: an Inupiat Journey in Science

    Dr. Kathryn Milligan-Myhre works in the field of host-microbe interactions. In this mSphere of Influence article, she reflects on the people and scientific ideas that influenced her journey from a small town in Alaska to a faculty position at the University of Alaska Anchorage.

    Kathryn C. A. Milligan-Myhre
  • Open Access
    Gut Microbial Dynamics during Conventionalization of Germfree Chicken
    Research Article | Host-Microbe Biology
    Gut Microbial Dynamics during Conventionalization of Germfree Chicken

    The domestic chicken is the cornerstone of animal agriculture worldwide, with a flock population exceeding 40 billion birds/year. It serves as an economically valuable source of protein globally. The microbiome of poultry has important effects on chicken growth, feed conversion, immune status, and pathogen resistance. The aim of our research was to develop a gnotobiotic chicken model appropriate for the study chicken gut microbiota...

    Milton Thomas, Supapit Wongkuna, Sudeep Ghimire, Roshan Kumar, Linto Antony, Kinchel C. Doerner, Aaron Singery, Eric Nelson, Tofuko Woyengo, Surang Chankhamhaengdecha, Tavan Janvilisri, Joy Scaria

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