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iron homeostasis

  • Open Access
    The Transcription Factor VdHapX Controls Iron Homeostasis and Is Crucial for Virulence in the Vascular Pathogen <span class="named-content genus-species" id="named-content-1">Verticillium dahliae</span>
    Research Article | Host-Microbe Biology
    The Transcription Factor VdHapX Controls Iron Homeostasis and Is Crucial for Virulence in the Vascular Pathogen Verticillium dahliae

    This study demonstrated that VdHapX is a conserved protein that mediates adaptation to iron starvation and excesses, affects microsclerotium formation, and is crucial for virulence of V. dahliae.

    Yonglin Wang, Chenglin Deng, Longyan Tian, Dianguang Xiong, Chengming Tian, Steven J. Klosterman
  • Open Access
    Multiple Evolutionarily Conserved Domains of Cap2 Are Required for Promoter Recruitment and Iron Homeostasis Gene Regulation
    Research Article | Molecular Biology and Physiology
    Multiple Evolutionarily Conserved Domains of Cap2 Are Required for Promoter Recruitment and Iron Homeostasis Gene Regulation

    Iron is an essential micronutrient for living cells. Candida albicans, the predominant human fungal pathogen, thrives under diverse environments with vastly different iron levels in the mammalian host. Therefore, to tightly control iron homeostasis, C. albicans has evolved a set of transcriptional...

    Manjit Kumar Srivastav, Neha Agarwal, Krishnamurthy Natarajan
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