Illumina
- Resource Report | Host-Microbe BiologyFusobacterium Genomics Using MinION and Illumina Sequencing Enables Genome Completion and Correction
Fusobacterium spp. are Gram-negative, oral bacteria that are increasingly associated with human pathologies as diverse as periodontitis, preterm birth, and colorectal cancer. While a recent surge in F. nucleatum research has increased our understanding of this human pathogen, a lack of complete genomes has hindered the identification and characterization of...
- Research Article | Host-Microbe BiologyA Multicenter Study To Evaluate the Performance of High-Throughput Sequencing for Virus Detection
Recent high-throughput sequencing (HTS) investigations have resulted in unexpected discoveries of known and novel viruses in a variety of sample types, including research materials, clinical materials, and biological products. Therefore, HTS can be a powerful tool for supplementing current methods for demonstrating the absence of adventitious or unwanted viruses in biological products, particularly when using a new cell line. However,...