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Fusobacterium

  • Open Access
    FusoPortal: an Interactive Repository of Hybrid MinION-Sequenced <em>Fusobacterium</em> Genomes Improves Gene Identification and Characterization
    Resource Report | Host-Microbe Biology
    FusoPortal: an Interactive Repository of Hybrid MinION-Sequenced Fusobacterium Genomes Improves Gene Identification and Characterization

    In this report, we describe a hybrid MinION whole-genome sequencing pipeline and the genomic characteristics of the first eight Fusobacterium strains deposited in the FusoPortal database. This collection of highly accurate and complete genomes drastically improves upon previous multicontig assemblies by correcting and newly identifying a significant number of open reading frames. We believe that the availability of this...

    Blake E. Sanders, Ariana Umana, Justin A. Lemkul, Daniel J. Slade
  • Open Access
    <em>Fusobacterium</em> Genomics Using MinION and Illumina Sequencing Enables Genome Completion and Correction
    Resource Report | Host-Microbe Biology
    Fusobacterium Genomics Using MinION and Illumina Sequencing Enables Genome Completion and Correction

    Fusobacterium spp. are Gram-negative, oral bacteria that are increasingly associated with human pathologies as diverse as periodontitis, preterm birth, and colorectal cancer. While a recent surge in F. nucleatum research has increased our understanding of this human pathogen, a lack of complete genomes has hindered the identification and characterization of...

    S. Michelle Todd, Robert E. Settlage, Kevin K. Lahmers, Daniel J. Slade
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