experimental evolution
Commentary | Therapeutics and PreventionmSphere of Influence: Evolutionary Strategies To Sensitize Drug-Resistant PathogensRebecca S. Shapiro studies antimicrobial resistance and genetic interaction networks. In this mSphere of Influence article, she reflects on how the papers “Bacterial evolution of antibiotic hypersensitivity” by Lázár et al. (V. Lázár, G. Pal Singh, R. Spohn, I.
Research Article | Ecological and Evolutionary ScienceEvolution of Cost-Free Resistance under Fluctuating Drug Selection in Pseudomonas aeruginosaAntibiotic resistance is a global problem that greatly impacts human health. How resistance persists, even in the absence of antibiotic treatment, is thus a public health problem of utmost importance. In this study, we explored the antibiotic treatment conditions under which cost-free resistance arises, using experimental evolution of the bacterium Pseudomonas aeruginosa...