TABLE 2

Gene expression analysis of S. aureus DAPs CB1631 compared with DAPr CB1634 using RNA-seq

ORFGeneProduct or functionFold change
SA1844agrAAccessory gene regulator A4.501
SA1842agrBAccessory gene regulator B1.984
SA1843agrCAccessory gene regulator C2.218
SAS066agrDAccessory gene regulator R2.424
SA2457capACapsular polysaccharide biosynthesis protein Cap5A1.359
SA0145capBCapsular polysaccharide biosynthesis protein Cap5B4.856
SA0146capCCapsular polysaccharide biosynthesis protein Cap5C1.444
SA0147capDCapsular polysaccharide biosynthesis protein Cap5D2.363
SA0148capECapsular polysaccharide biosynthesis protein Cap5E2.672
SA0149capFCapsular polysaccharide biosynthesis protein Cap5F2.425
SA0150capGCapsular polysaccharide biosynthesis protein Cap5G1.798
SA0151capHCapsular polysaccharide biosynthesis protein Cap5H3.642
SA0152capICapsular polysaccharide biosynthesis protein Cap5I1.641
SA0153capJCapsular polysaccharide biosynthesis protein Cap5J1.288
SA0154capKCapsular polysaccharide biosynthesis protein Cap5K1.99
SA0155capLCapsular polysaccharide biosynthesis protein Cap5L1.213
SA0156capMCapsular polysaccharide biosynthesis protein Cap5M1.217
SA0157capNCapsular polysaccharide biosynthesis protein Cap5N2.879
SA0159capPCapsular polysaccharide biosynthesis protein Cap5P1.259
SA0742clfAClumping factor A, fibrinogen binding protein−1.977
SA2423clfBClumping factor B, fibrinogen binding protein1.039
SA0222coaStaphylocoagulase precursor2.458
SA2291fnbAFibronectin binding protein A1.742
SA2290fnbBFibronectin binding protein B2.692
SA0309gehLipase1.274
SA1756hlbTruncated β-hemolysin3.075
SAS065hldδ-Hemolysin8.235
SA2207hlgAγ-Hemolysin component A1.412
SA2209hlgBγ-Hemolysin component B2.195
SA2208hlgCγ-Hemolysin component C1.476
SA2356isaAImmunodominant antigen A2.629
SA0977isdAIron-regulated surface determinant protein A2.582
SA0976isdBIron-regulated surface determinant protein B2.841
SA0979isdDIron-regulated surface determinant protein D3.817
SA0980isdEIron-regulated surface determinant protein E2.702
SA1637lukDLeukotoxin3.537
SA1638lukELeukotoxin3.515
SA0661saeRResponse regulator SaeR4.824
SA0660saeSSensor histidine kinase SaeS3.078
SA2206sbiImmunoglobulin G binding protein4.546
SA0519sdrCSerine-aspartate repeat-containing protein C, fibrinogen binding protein1.171
SA0520sdrDSerine-aspartate repeat-containing protein D, fibrinogen binding protein1.316
SA0521sdrESerine-aspartate repeat-containing protein E, fibrinogen binding protein1.165
SA1869sigBRNA polymerase sigma factor1.066
SA0107spaProtein A−1.264
SA1631splASerine protease4.269
SA1630splBSerine protease2.244
SA1629splCSerine protease1.147
SA1628splDSerine protease3.059
SA2093ssaAStaphylococcal secretory antigen2.6
SA1700vraRResponse regulator VraR−3.021
SA1701vraSSensor protein VraS−1.816
SA0018walKSensor protein kinase WalK (VicK, YycG)−1.122
SA0017walRResponse regulator WalR (VicR, YycF)−1.289