TABLE 3

High-confidence genes involved in yeast-to-hyphae transitiona

JGI protein IDS. cerevisiae BlastPbNo. of strainsPredicted mutations recovered
113409sln1 (nik1)5E342G, S441T, I536M, G584S, M598K
140296cts14K2*, W134*, G285E, G284V/E837D
127631ssk23G1190D, P555H, R526P
109080sln1 (chk1)2T1290M, E1415K
122144pbs222 x G371R
124736hog11S335*
128138hym11L103P
131882lrg11G938C
129277mih11Y476*
  • a Genes with mutations in independent mutant strains as well as genes found in only one strain but with few or no other nonsynonymous mutations. Eight mutant strains contained many nonsynonymous mutations in unique gene hits and are not shown.

  • b Genes in parentheses represent the best BlastP hit from C. albicans.