TABLE 2

LD50 values for bacterial strains via the i.p. route

StrainVariantGenotypeLD50 (CFU)
CMF 6999Sensu strictoWild type1.4 × 106
CDC00-0301JavaWild type8.0 × 105
CVD 2003Sensu strictoCMF 6999 ΔguaBA>5 × 108
CVD 2004Sensu strictoCMF 6999 ΔclpX4.25 × 107
CVD 2005Sensu strictoCMF 6999 ΔguaBA ΔclpX>5 × 108