TABLE 3

Vaccine efficacy of strain CVD 2005 against lethal challenge

Immunization
route
ImmunizationChallengeaMortality
rate
Time to deathVaccine efficacy
Mean
(days)
P value (Student’s
t test)
% efficacyP value (Fisher’s
exact test)
p.o.PBSSensu stricto10/122NSb90<0.001
CVD 2005Sensu stricto1/124
i.n.PBSSensu stricto10/122NAc100<0.001
CVD 2005Sensu stricto0/12NA
PBSJava12/1210.016420.037
CVD 2005Java7/1210
PBSTyphimurium10/1211NS0NS
CVD 2005Typhimurium12/1215
  • a Represented are S. Paratyphi B sensu stricto strain CMF 6999, S. Paratyphi B Java strain CDC00-0301, and S. Typhimurium strain I77.

  • b NS, not significant (P > 0.05).

  • c NA, not applicable.