The fold change and adjusted P values from the SS (+glc +AA) versus SS (−glc +AA) DGE comparison for top genes changing toward or against progression

Gene IDGene productaLogFC (LS vs PF)bAdj. P valuecLogFC (SS+glc vs SS−glc)dAdj. P valuec
Toward progression
Against progression
  • a GPEET, GPEET procyclin; gMDH, glycosomal malate dehydrogenase; EP1, EP1 procyclin; PPDK, pyruvate phosphate dikinase; mMDH, mitochondrial malate dehydrogenase; EP3-2, EP3-2 procyclin; PAD2, protein associated with differentiation 2; FHc, cytosolic fumarate hydratase; PRODH, proline dehydrogenase; GDH, glutamate dehydrogenase; VSG, variant surface glycoprotein; ALD, fructose-bisphosphate aldolase; PFK, ATP-dependent 6-phosphofructokinase; PYK1, pyruvate kinase 1; PDI2, protein disulfide isomerase 2; ENO, enolase; PGI, glucose-6-phosphate isomerase; PGKC, phosphoglycerate kinase C; DHH1, DExD/H-box ATP-dependent RNA helicase.

  • b LogFC (LS vs PF), the log2 fold change value of transcripts from LS incubated in glucose-rich media compared to that from PF very-low-glucose media.

  • c Adjusted P value was calculated using the Benjamini-Hochberg method on P values generated by likelihood ratio.

  • d LogFC (SS+glc vs SS−glc), the log2 fold change value of transcripts from SS incubated in very-low-glucose media compared to that from SS in glucose-rich media.