TABLE 1

Selleck library small-colony variant (SCV) screening hits

DrugAvg fold change in AK signal (SD)a
10-DAB (10-deacetylbaccatin)1.52 (±0.65)
Amitriptyline1.44 (±0.49)
Ammonium glycyrrhizinate (AMGZ)1.58 (±0.86)
Apatinib1.71 (±1.03)
Cidofovir1.17 (±0.03)
Clonidine hydrochloride1.66 (±1.02)
Daunorubicin1.44 (±0.30)
Esomeprazole1.78 (±1.06)
Furosemide1.24 (±0.25)
Genistein1.32 (±0.08)
Ketoconazole1.30 (±0.07)
Mepivacaine1.45 (±0.57)
Methocarbamol1.24 (±0.05)
Milrinone (Primacor)1.62 (±0.86)
Mizolastine (Mizollen)1.59 (±0.95)
Olanzapine (Zyprexa)1.50 (±0.67)
Pantothenic acid1.73 (±0.99)
Pomalidomide1.20 (±0.15)
Rifapentine1.18 (±0.08)
Sitafloxacin1.42 (±0.58)
Sulbactam1.26 (±0.36)
Sulfamethazine1.47 (±0.51)
  • a Data represent average fold increase in adenylate kinase (AK) release in comparison to mock-treated control.