TABLE 2 

Correlation of C. trachomatis and C. pneumoniae peptide reactivities with species-specific MIF titers

Peptide setaChlamydia species specificitySource proteinsAntibody isotypeCorrelation tob:
C. trachomatis MIF titerC. pneumoniae MIF titerPeptide set 1
PRPRPR
1 (peptides 1–11)C. trachomatisOmpA, TarP, CT143, PmpD. IncE, CT529, CT442, CT618IgG110−40.560.91
2 (peptides 12–22)C. trachomatisCT813, LcrE, CT226, IncE, IncG, CT223, CT618, CT795, PmpCIgG110−30.470.20<10−60.81
3 (peptides 23–34)C. trachomatisOmpA, variable domains (VD) 1, 2, 3, 4IgG10.020.330.3210−50.65
3 (peptides 23–34)C. trachomatisOmpA (VD1 to VD4)IgG30.010.360.1210−50.60
4 (peptides 35–38)C. trachomatisHsp60, pGP3IgG10.420.920.0020.44
5 (peptides 39–50)C. pneumoniaeIncA, PmpD, PmpG/I, CT618, PmpG, Cpn0525, YscCIgG10.660.390.0030.42
  • a Peptide sets and peptide numbers are identical to those of the peptides shown in Fig. 6.

  • b Pearson’s correlation coefficient (R) and P values were calculated in linear regression analyses. The correlations are based on the mean reactivity of a peptide set with each of 48 individual sera (Fig. 6). –, absence of significant correlation or self-comparison.