TABLE 3 

Transcriptional analysis of functionally related gene families that exhibit a nonrandom genomic distribution in S. cerevisiae

DescriptionGO no.Gene set sizeNo. clusteredP valuePCC fora:
SingletonsClusters
Vitamin metabolic processGO:000676643119.06E−130.10050.507
Cell wall organization or biogenesisGO:0071554198388.35E−100.0440.155
SporulationGO:0043934133205.09E−070.0430.4626
Meiotic cell cycleGO:0051321282498.53E−060.03540.2281
Phosphatase activityGO:001679195121.10E−050.04060.5193
RibosomeGO:0005840343627.90E−050.11530.264
Structural constituent of ribosomeGO:0003735236351.01E−040.16670.0907
Monocarboxylic acid metabolic processGO:0032787141171.29E−040.05230.5586
Amino acid transportGO:00068654647.34E−040.11480.2534
Lipid transportGO:00068696869.55E−040.0429−0.1973
DNA replicationGO:0006260139142.21E−030.09910.2963
Chromatin organizationGO:0006325318492.61E−030.07180.1108
Translational initiationGO:00064135443.00E−030.13750.0586
Peptidase activityGO:00082339483.01E−030.10.3957
Pseudohyphal growthGO:00071245644.16E−030.01260.6038
Extracellular regionGO:00055763124.17E−030.0413−0.5761
Telomere organizationGO:00322007864.51E−030.05650.7413
Methyltransferase activityGO:00081689076.10E−030.1190.6294
tRNA aminoacylation for protein translationGO:00064183629.57E−030.09660.7101
Protein glycosylationGO:00064866249.69E−030.19170.6667
rRNA processingGO:0006364236281.12E−020.35110.338
Helicase activityGO:00043868661.26E−020.10960.6232
Regulation of cell cycleGO:0051726232271.28E−020.04110.047
Cytoskeleton organizationGO:0007010238281.39E−020.06620.0753
Regulation of DNA metabolic processGO:005105210781.54E−020.05840.4021
Nucleus organizationGO:00069976641.60E−020.09060.1009
Cytoskeletal protein bindingGO:00080926741.79E−020.0539−0.2497
Lyase activityGO:00168299061.98E−020.05450.5955
Nuclease activityGO:00045189262.44E−020.07880.0358
DNA-templated transcription, initiationGO:00063527343.43E−020.1060.3507
Hydrolase activity, acting on glycosyl bondsGO:00167984723.88E−020.0515−0.0869
Cofactor metabolic processGO:0051186179164.09E−020.09280.1328
Guanyl-nucleotide exchange factor activityGO:00050854824.30E−020.0662−0.6026
DNA repairGO:0006281256294.63E−020.050.2181
Transmembrane transportGO:0055085235254.69E−020.08690.4296
ExocytosisGO:00068874724.77E−020.62510.0608
Nuclear transportGO:0051169181164.85E−020.16140.2033
Cellular budGO:0005933241264.92E−020.0470.1037
  • a PCC, Pearson’s correlation coefficient following expression throughout the cell cycle (24).