TABLE 3

Common mutations acquired by A. baumannii strains resistant to 4F

Mutation in lineagea:GeneProduct
12345
ΧΧΧΧΧpla1Phospholipase A1
ΧΧpldPhospholipase D
ΧbΧΧadeSSensor histidine kinase
ΧΧΧpgsACDP-diacylglycerol-glycerol-3-phosphate
3-phosphatidyltransferase
  • a This table lists only those mutations that were acquired by two or more lineages. Three strains were sequenced per lineage. The symbol “Χ” denotes genes that are disrupted in all three sequenced strains within a lineage.

  • b Two out of three sequenced strains in lineage 3 show mutations in the adeS gene.