TABLE 2

HMO profiles in milk collected at postnatal day 21

HMOaMean (SD) HMO concn (mg/ml)Corrected
P valueb
CON (n = 32)EVC001-fed (n = 34)
Total14.37 (2.80)13.81 (0.43)NS
2′-FL1.62 (0.97)1.71 (1.04)NS
3′-FL0.5 (0.33)0.55 (0.05)NS
30000.18 (0.17)0.18 (0.06)NS
LDFT0.11 (0.02)0.15 (0.03)NS
LNT, LNnT3.35 (0.31)2.89 (0.24)NS
LNFP I2.05 (0.31)1.85 (0.27)NS
LNFP II, III, V1.12 (0.13)1.09 (0.12)NS
3′-SLN, 6′-SLN0.01 (0)0.01 (0)NS
LNH, LNnH0.47 (0.05)0.4 (0.03)NS
LNDFH I, II0.21 (0.03)0.23 (0.02)NS
3′-SL, 6′-SL1.54 (0.07)1.62 (0.07)NS
MFLNH, IFLNH0.78 (0.04)0.77 (0.04)NS
43000.05 (0)0.04 (0)NS
42200.31 (0.02)0.31 (0.01)NS
53100.18 (0.01)0.15 (0.01)NS
LSTa, b, c0.31 (0.02)0.31 (0.02)NS
42300.08 (0.01)0.09 (0.01)NS
53200.2 (0.01)0.18 (0.01)NS
64100.14 (0.01)0.14 (0.01)NS
31110.01 (0)0.01 (0)NS
53300.12 (0.01)0.11 (0)NS
42010.32 (0.03)0.3 (0.03)NS
64200.11 (0.01)0.1 (0.01)NS
53400.02 (0)0.02 (0)NS
42110.47 (0.03)0.47 (0.02)NS
64400.02 (0)0.02 (0)NS
53010.01 (0)0.01 (0)NS
53110.04 (0)0.04 (0)NS
64010.02 (0)0.02 (0)NS
53210.02 (0)0.02 (0)NS
64300.02 (0)0.02 (0)NS
42210.01 (0)0.01 (0)NS
53310 (0)0 (0)NS
  • a Abbreviations: 2′-FL, 2′-fucosyllactose; 3′-FL, 3′-fucosyllactose; LDFT, lacto-difucosyltetraose; LNT, lacto-N-tetraose; LNnT, lacto-N-neotetraose; LNFP, lacto-N-fucosyllpentose; SLN, sialyllactosamine; LNH, lacto-N-hexose; LNnH, lacto-N-neohexose; DFLNH, difucosyllacto-N-hexose; MFLNH, mono-fucosyllacto-N-hexose; IFLNH, isomeric fucoysllactosyl-N-hexose; LST, sialyl-lacto-N-tetraose; LSTa, b, c, isomers of LST. Structural formula for unnamed structures is hexose | hexose-N-acetylglucosamine/galactosamine | fucose | sialic acid.

  • b P values were determined with a multiple t test and the Holm-Sidak correction. NS, not significant.