Culture results for infected and noninfected TIVAP chambers from the two hospital cohorts and species (OTU) richness as detected by 16S clone library generationa

TIVAP group and
sample ID
No. of
No. of OTUs detected
in 16S clone library
No. of clones generated
for 16S clone library
Curie symptomatic
    CS-2 Staphylococcus aureus* >1,000148
    CS-3 Staphylococcus epidermidis* 200148
    CS-4 Staphylococcus epidermidis* >1,000148
    CS-5 Staphylococcus epidermidis* >1,000148
    CS-6 Candida parapsilosis >1,000548
    CS-8 Staphylococcus aureus* 130645
    CS-9 Staphylococcus xylosus <10449
    CS-10 Candida krusei and Staphylococcus epidermidis* >1,000148
Curie asymptomatic
    CA-7 Staphylococcus epidermidis 20348
Limoges symptomatic
    LS-1 Staphylococcus epidermidis*,
Bacillus simplex
1, 1150
    LS-3 Enterobacter cloacae* >500150
    LS-4(Staphylococcus epidermidis on
distal catheter)
    LS-5 Staphylococcus epidermidis* >500150
    LS-6 Escherichia coli* >500150
    LS-7 Staphylococcus aureus* <50149
    LS-8 Staphylococcus aureus* 1448
    LS-9 Pseudomonas aeruginosa* <50149
    LS-10 Staphylococcus epidermidis* <10249
Limoges asymptomatic
    LA-6 Micrococcus luteus 1650
    LA-7 Micrococcus luteus 1350
  • a Species shown in bold with an asterisk represent the cultured organism that was also the dominant organism detected in the 16S rRNA gene clone library. The bacteria isolated from the TIVAP samples of symptomatic patients were also isolated from the blood cultures.