TABLE 3

Putative genomic markers associated with pH and salinity optima

KO IDaOptimumDescriptioncSign of coefficientTCDBb present
K01546BothK+-transporting ATPase ATPase A chainYes
K01547BothK+-transporting ATPase ATPase B chainYes
K01548BothK+-transporting ATPase ATPase C chainYes
K03310BothAlanine or glycine:cation symporter, AGCS family+Yes
K03499BothTrk system potassium uptake protein+Yes
K07301BothCation:H+ antiporter+Yes
K08974BothPutative membrane protein+No
K03543pHMembrane fusion protein, multidrug efflux systemYes
K03446pHMFS transporter, DHA2 family, multidrug resistance proteinYes
K08677pHKumamolisinNo
K07799pHMembrane fusion protein, multidrug efflux systemYes
K06045pHSqualene-hopene/tetraprenyl-beta-curcumene cyclaseYes
K15495pHMolybdate/tungstate transport system substrate-binding proteinYes
K15496pHMolybdate/tungstate transport system permease proteinYes
K14393pHCation/acetate symporter+Yes
K02168pHCholine/glycine/proline betaine transport protein+Yes
K07393pHPutative glutathione S-transferase+No
K06718pHl-2,4-Diaminobutyric acid acetyltransferase+No
K06720pHl-Ectoine synthase+No
K09908pHUncharacterized protein+No
K06213pHMagnesium transporter+Yes
K05565pHMulticomponent Na+:H+ antiporter subunit A+Yes
K05567pHMulticomponent Na+:H+ antiporter subunit C+Yes
K05568pHMulticomponent Na+:H+ antiporter subunit D+Yes
K05569pHMulticomponent Na+:H+ antiporter subunit E+Yes
K05570pHMulticomponent Na+:H+ antiporter subunit F+Yes
K05571pHMulticomponent Na+:H+ antiporter subunit G+Yes
K14683pHSolute carrier family 34 (sodium-dependent phosphate cotransporter)+Yes
K14445pHSolute carrier family 13 (sodium-dependent dicarboxylate transporter), member 2/3/5+Yes
K03451pHBetaine/carnitine transporter, BCCT family+Yes
K03308pHNeurotransmitter:Na+ symporter, NSS family+Yes
K08714pHVoltage-gated sodium channel+Yes
K03826pHPutative acetyltransferase+No
K03975SalinityMembrane-associated proteinYes
K08223SalinityMFS transporter, fosmidomycin resistance proteinYes
K07646SalinityTwo-component system, OmpR family, sensor histidine kinase KdpDNo
K03549SalinityKUP system potassium uptake proteinYes
K03699SalinityPutative hemolysinNo
K02276SalinityCytochrome c oxidase subunit III+No
K07160SalinityUPF0271 protein+No
  • a KO ID, entry in KEGG ortholog (KO) database.

  • b TCDB indicates whether the enriched KO was included in the Transporter Classification Database.

  • c Abbreviations: AGCS, alanine or glycine cation symporter; MFS, major facilitator superfamily; BCCT, betaine carnitine choline transporter; NSS, neurotransmitter sodium symporter; KUP, K uptake permease.