TABLE 3

Putative genomic markers associated with pH and salinity optima

KO IDaOptimumDescriptioncSign of coefficientTCDBb present
K01546 BothK+-transporting ATPase ATPase A chainYes
K01547 BothK+-transporting ATPase ATPase B chainYes
K01548 BothK+-transporting ATPase ATPase C chainYes
K03310 BothAlanine or glycine:cation symporter, AGCS family+Yes
K03499 BothTrk system potassium uptake protein+Yes
K07301 BothCation:H+ antiporter+Yes
K08974 BothPutative membrane protein+No
K03543 pHMembrane fusion protein, multidrug efflux systemYes
K03446 pHMFS transporter, DHA2 family, multidrug resistance proteinYes
K08677 pHKumamolisinNo
K07799 pHMembrane fusion protein, multidrug efflux systemYes
K06045 pHSqualene-hopene/tetraprenyl-beta-curcumene cyclaseYes
K15495 pHMolybdate/tungstate transport system substrate-binding proteinYes
K15496 pHMolybdate/tungstate transport system permease proteinYes
K14393 pHCation/acetate symporter+Yes
K02168 pHCholine/glycine/proline betaine transport protein+Yes
K07393 pHPutative glutathione S-transferase+No
K06718 pH l-2,4-Diaminobutyric acid acetyltransferase+No
K06720 pH l-Ectoine synthase+No
K09908 pHUncharacterized protein+No
K06213 pHMagnesium transporter+Yes
K05565 pHMulticomponent Na+:H+ antiporter subunit A+Yes
K05567 pHMulticomponent Na+:H+ antiporter subunit C+Yes
K05568 pHMulticomponent Na+:H+ antiporter subunit D+Yes
K05569 pHMulticomponent Na+:H+ antiporter subunit E+Yes
K05570 pHMulticomponent Na+:H+ antiporter subunit F+Yes
K05571 pHMulticomponent Na+:H+ antiporter subunit G+Yes
K14683 pHSolute carrier family 34 (sodium-dependent phosphate cotransporter)+Yes
K14445 pHSolute carrier family 13 (sodium-dependent dicarboxylate transporter), member 2/3/5+Yes
K03451 pHBetaine/carnitine transporter, BCCT family+Yes
K03308 pHNeurotransmitter:Na+ symporter, NSS family+Yes
K08714 pHVoltage-gated sodium channel+Yes
K03826 pHPutative acetyltransferase+No
K03975 SalinityMembrane-associated proteinYes
K08223 SalinityMFS transporter, fosmidomycin resistance proteinYes
K07646 SalinityTwo-component system, OmpR family, sensor histidine kinase KdpDNo
K03549 SalinityKUP system potassium uptake proteinYes
K03699 SalinityPutative hemolysinNo
K02276 SalinityCytochrome c oxidase subunit III+No
K07160 SalinityUPF0271 protein+No
  • a KO ID, entry in KEGG ortholog (KO) database.

  • b TCDB indicates whether the enriched KO was included in the Transporter Classification Database.

  • c Abbreviations: AGCS, alanine or glycine cation symporter; MFS, major facilitator superfamily; BCCT, betaine carnitine choline transporter; NSS, neurotransmitter sodium symporter; KUP, K uptake permease.