Transformation efficiency with and without RNPs in three Candida species

SpeciesSample no.Gene deletion constructRNPNo. of Natr transformantsaP value for difference between + and − RNPsb
C. lusitaniae 1+12
C. lusitaniae 2++112<0.05
C. auris 3+680
C. auris 4++3,880<0.05
C. glabrata 5+1,857
C. glabrata 6++36,400<0.01
  • a The number of transformants represents the average from 3 or 4 independent transformations.

  • b Significance determined by ratio-paired t test.