Transformation efficiency with and without RNPs in three Candida species

SpeciesSample no.Gene deletion constructRNPNo. of Natr transformantsaP value for difference between + and − RNPsb
C. lusitaniae1+12
C. lusitaniae2++112<0.05
C. auris3+680
C. auris4++3,880<0.05
C. glabrata5+1,857
C. glabrata6++36,400<0.01
  • a The number of transformants represents the average from 3 or 4 independent transformations.

  • b Significance determined by ratio-paired t test.