TABLE 1

Bacterial strainsa

Species and isolate no.bDate of isolation (day/mo/yr)SiteSTMIC (µg/ml)TET/CLO/ERY susceptibility
PEN-GCTXOXA
S. pneumoniae (ST23F)
    D12227/07/1992Nasopharynx105230.19–0.250.125–0.194–6S/S/S
    D1278/4/1994Nasopharynx105230.19–0.250.125–0.194–6S/S/S
    D12825/07/1994Nasopharynx105230.19–0.250.125–0.194–6S/S/S
    D13431/10/1994Nasopharynx105230.19–0.250.125–0.194–6S/S/S
    D1369/1/1995Nasopharynx105230.19–0.250.125–0.194–6S/S/S
    D1399/5/1995Sputum105230.19–0.250.125–0.19NDdS/S/S
    D1411/8/1995Nasopharynx105230.19–0.250.125–0.194–6S/S/S
    D2191989Throat105230.19–0.250.125–0.19NDS/S/S
S. mitis
    B81995Oral cavity0.12–0.20.006–0.030.5S/S/S
    B93-4c1995Oral cavityNDNDNDND
    B101995Oral cavity0.470.230.38S/S/S
S. oralis
    B111995Oral cavity8296R/S/(R)
  • a S, sensitive; R, resistant; (R) intermediate resistant. Drug abbreviations: PEN-G, benzylpenicillin; CTX, cefotaxime; OXA, oxacillin; TET, tetracycline; CLO, chloramphenicol; ERY, erythromycin.

  • b All isolates were obtained from the Wannsee-Lungenklinik-Heckeshorn, Berlin, and from the same patient, except for D219, which was isolated in Leipzig (25).

  • c The strain could not be recovered after DNA isolation.

  • d ND, not determined.