TABLE 3 

The pathogenic potential of a microbe varies with the genetic background of the mouse straina

MicrobeMouse strainMortalityInoculumPPReference
L. monocytogenesC57BL/60.59.0 × 1053.5 × 10−639
B10.D20.52.2 × 1051.4 × 10−539
B10.A0.52.2 × 1051.4 × 10−539
BALB/c0.53.9 × 1038.1 × 10−339
CBA0.55.0 × 1036.3 × 10−439
A/WySn0.58.0 × 1034.0 × 10−439
(C57BL/6 × BALB/c)F10.53.4 × 1049.3 × 10−539
B. anthracisA/J0.52.6 × 1001.2 × 10040
C3H/HeJ0.55.6 × 1005.6 × 10−140
BALB/cJ0.56.6 × 1004.8 × 10−140
C58J0.59.0 × 1003.5 × 10−140
C57BL/6J0.51.4 × 1012.3 × 10−140
C57L/J0.52.2 × 1011.4 × 10−140
Sendai virus129/ReJ 10.53.2 × 1009.9 × 10−141
SWR/J0.55.0 × 1026.3 × 10−341
C58/J0.51.5 × 1032.1 × 10−341
C57BL/6J0.52.5 × 1041.3 × 10−441
SJL/J0.51.0 × 1053.2 × 10−541
C. immitisBALB/cAnN0.54.6 × 1016.9 × 10−217
C57BL/10N0.55.9 × 1025.4 × 10−317
C57BL/6N0.56.8 × 1024.7 × 10−317
DBA/2NX10.51.8 × 1051.8 × 10−517
  • a The PP calculation used literature information for the mortality of mice infected with these microbes. For the PP calculation, Fs was assumed to 1.0 in all instances, which means that the PP reduces to the inverse of the inoculum modified by the mortality parameter. The PP calculations in this table are for illustrative purposes only, and the reader is cautioned that the studies listed above used different infection conditions. Hence, comparisons among the listed microbes should be done cautiously, and the major goal of the listing in this table is to show that how the changing the host can change the PP.