TABLE 1 

Analysis of pathogenic potential of Salmonella enterica serovar Typhimurium in mice based on mortality dataa

StrainResult for inoculum ofb:
5 × 1075 × 1065 × 1055 × 1045 × 103
MPPMPPMPPMPPMPP
2201c1.01.7 × 10−71.01.7 × 10−60.55.3 × 10−60.55.3 × 10−50.00
22021.02.0 × 10−70.81.3 × 10−60.68.0 × 10−60.12.5 × 10−50.00
2203d1.02.5 × 10−71.02.5 × 10−60.92.0 × 10−50.24.0 × 10−50.00
22040.81.3 × 10−70.71.0 × 10−60.12.5 × 10−60.000.00
22050.81.3 × 10−70.56.3 × 10−70.23.2 × 10−60.23.2 × 10−50.00
22061.02.0 × 10−70.91.6 × 10−60.23.2 × 10−60.000.00
  • a The original data were published in Table 2 in reference 4. There was no specific reason for selecting this study apart from that it included sufficient data to make the point that PP can discriminate in situations where the LD50 does not discriminate, as is evident for strain 2201, where 50% mortality was obtained with inocula that differed by 10-fold.

  • b M stands for mortality, and the numbers given are the fractional mortality data for 10 mice. In calculating the PP, the Fs was assumed to be 1.0 under all conditions where there was at least one death and 0.0 when no death was observed.

  • c The infective inocula for this strain were subsequently found to be 6 × 107, 6 × 106, etc.

  • d The infective inocula for this strain were subsequently found to be 4 × 107, 4 × 106, etc.