TABLE 1

Demographic characteristics of patients with and without infection

VariableNo. (%) or mean ± SDP valuea
Infected (n = 39)No infection (n = 1,726)
Female19 (48.7)835 (48.3)>0.99
White race31 (79.5)1,438 (83.3)0.488
Hispanic0 (0)33 (1.9)0.984
Prior admit (28 days)27 (69.2)947 (54.8)0.079
Length of stay (days)14.9 ± 14.911.6 ± 18.90.01
Neurologic disorderb6 (15.4)109 (6.3)0.029
Fluid and electrolyte disorderb20 (51.3)569 (33)0.019
Renal diseaseb5 (12.8)286 (16.6)0.533
Liver diseaseb5 (12.8)112 (6.5)0.123
Alcohol abuseb1 (2.6)94 (5.4)0.442
Solid organ tumorb13 (33.3)403 (23.3)0.151
Diabetes mellitus, uncomplicatedb8 (20.5)242 (14)0.218
K. pneumoniae colonization21 (53.8)385 (22.3)<0.001
Central line before colonization27 (69.2)963 (55.8)0.099
Antibiotic exposurec5 (12.8)453 (26.2)0.067
    Aminoglycoside0 (0)178 (10.3)0.984
    Fluoroquinolone0 (0)0 (0)NA
    Macrolide2 (5.1)151 (8.7)0.433
    Cephalosporin1 (2.6)139 (8.1)0.237
    Carbapenem0 (0)0 (0)NA
    Clindamycin2 (5.1)97 (5.6)0.895
Age (yrs)62.7 ± 12.858.2 ± 16.10.078
Hemoglobin, baseline (g/dl)10.4 ± 2.411.1 ± 2.50.062
Platelets, baseline (×103/µl)167.9 ± 90.9207.3 ± 115.50.012
Albumin, baseline (g/dl)3.3 ± 0.63.5 ± 0.60.009
Body mass index (kg/m2)27 ± 6.729.5 ± 9.50.128
  • a P values were obtained using Student’s t test for continuous variables and the chi-square or Fisher's exact test for categorical variables.

  • b As defined by the Elixhauser index (35).

  • c All classes combined, with receipt before colonization; selected individual classes are also listed.