TABLEĀ 1

Known and putative mechanisms of ionophore resistance

AntibioticMechanismOrganismGenetic basis known?Reference
TetronasinEffluxStreptomyces longisporoflavusYes36
NarasinEfflux (putative)VREYes38
TetronasinPermeabilityPrevotella ruminicolaNo29
MonensinCell wall thickeningEnterococcus spp., C. perfringensNo39
MonensinIncreased extracellular polysaccharideC. aminophilumNo40