TABLE 5

Metatranscriptomic MaAsLin enrichment results with relative abundance quartiles

PathwayEnrichment (CPM) for:CoefficientEnrichment
group
P valueFDR-corrected
P value
CDI Q1CDI Q3CDI+ Q1CDI+ Q3
Valine leucine and isoleucine biosynthesis9,514.1115,392.905,648.818,337.13−0.02054CDI0.0080.146
Carbon fixation in photosynthetic organisms10,333.6914,029.936,935.828,324.76−0.01236CDI0.0080.146
Protein processing in endoplasmic reticulum141.982,011.250.0035.63−0.0226CDI0.0240.255
Glycine serine and threonine metabolism17,065.7524,255.2113,585.1617,256.03−0.0103CDI0.0250.255
Histidine metabolism8,980.5413,015.116,643.918,720.96−0.01492CDI0.0320.301
One-carbon pool by folate8,894.9614,537.306,096.518,641.10−0.01285CDI0.0560.390
C branched dibasic acid metabolism5,504.799,086.764,008.126,235.85−0.01223CDI0.0590.392
Alpha-linolenic acid metabolism0.00207.16693.911,265.720.02426CDI+0.0000.029
Bacterial chemotaxis167.311,297.162,265.064,147.410.03489CDI+0.0000.029
Ascorbate and aldarate metabolism526.982,203.763,161.596,267.150.03851CDI+0.0000.029
Ethylbenzene degradation0.00180.42497.381,033.910.02145CDI+0.0010.029
Geraniol degradation0.00511.95848.861,080.130.02247CDI+0.0010.029
Flagellar assembly0.001,133.641,080.827,448.640.04871CDI+0.0010.029
Two-component system14,066.5521,493.1125,306.6040,448.820.06355CDI+0.0010.029
ABC transporters28,206.8244,320.1148,815.2159,718.370.05873CDI+0.0020.090
Sulfur relay system2,878.556,146.676,467.437,358.350.02199CDI+0.0030.090
Linoleic acid metabolism0.002.7220.77344.470.00917CDI+0.0030.090
Ether lipid metabolism0.0026.6120.77344.470.00915CDI+0.0030.090
Chlorocyclohexane and chlorobenzene degradation0.0021.93125.99506.710.01062CDI+0.0040.090
Biosynthesis of siderophore group nonribosomal
peptides
37.17647.97629.222,408.830.0236CDI+0.0050.120
Fluorobenzoate degradation0.005.3959.17392.770.01066CDI+0.0090.165
Sulfur metabolism4,620.159,094.607,747.3911,277.500.02683CDI+0.0100.165
Toluene degradation0.0033.1866.83336.920.0094CDI+0.0140.206
Quorum sensing14,686.7218,688.3918,603.7123,100.570.02664CDI+0.0230.255
Phosphotransferase system4,091.529,124.8911,965.6114,977.450.04152CDI+0.0290.279
Mitogen-activated protein kinase signaling pathway,
fly
0.00410.01403.971,096.530.01406CDI+0.0330.306
Lysine degradation527.142,350.371,856.782,798.060.0183CDI+0.0420.345
Proteasome0.005.990.00228.250.00495CDI+0.0540.390
Biofilm formation, Pseudomonas aeruginosa1.331,326.79989.981,979.080.01642CDI+0.0550.390