TABLE 1

Effects of incubation time and IPP on EC50 values from ring-initiated P. falciparum growth inhibition assaysa

CompoundMean EC50 (nM) ± SD for incubation time and IPP presence
48 h96 h
−IPP+IPP
AA74-1>1,00096 ± 3894 ± 39
Clindamycin>10,00037 ± 24>10,000
Chloroquine9.0 ± 2.48.5 ± 2.0ND
  • a Values are means from three biological replicates. ND, not determined.