TABLE 1

Characteristics of mobile genetic elementsa

MGESize
(kb)b
% G+C
content
Insertion
site
TypeAnalogue
(% identityc)
Distribution
(% prevalence rate)
Cargo genes
and functions
Prophages
    φSPU141.547.5thrWP22ST104 (100)Lineage I (93); lineage III (53);
lineage II (33)
Virulence, pipB3; LPS modification,
gtrA, gtrB, gtrC
    φSPU231.152.7yfiN-rplSP2PsP3 (90)6702d
    φSPU3e33.551.6ssrAP2Fels-2 (80)Lineage IV (100); lineage II (100);
lineage III (27); lineage I (1)
    φSPU429.653.2yiiP-cpxPP2P2 (97)N69d
Small plasmids
    pSPUS14.151.9ColE1ColE1 (98)Lineage I (99); lineage II (67);
lineage IV (63); lineage III (47)
Virulence, ipaJ
    pSPUS22.347.4ColE1fColE1 (83)Lineage I (94); lineage IV (88);
lineage II (67); lineage IIIg (60)
    pSPUS32.553.6RCRpVCM01 (99)Lineage III (100); lineage IV (88);
lineage I (87)
AMR plasmids
    pSPUR147.552.1IncNR46 (100)N46d,hResistance, dfrA17, aadA5h, sul1,
qacE, tet(A); RMS, ecoRIIR, ecoRIIM
    pSPUR273.247.6IncX1pOLA52 (98)N69dResistance, ars, sul2, blaTEM-1b, tet(A) h
    pSPUR348.446.7IncX1pOLA52 (95)N27dResistance, blaTEM-1b, tet(A) h
    pSPUR48.761.0IncQ1RSF1010 (100)N27dResistance, sul2, strAB
    pSPUR511.061.7IncQ1RSF1010 (100)N60d,hResistance, sul2, strAB, tet(A)
  • a RCR, rolling-circle replication; AMR, antimicrobial resistance; RMS, restriction-modification system.

  • b Data represent prophage sizes, including flanked direct repeats (DRs) within the bacterial attachment site (attB).

  • c Values represent global sequence identity for prophages and replicon sequence identity for plasmid.

  • d The indicated strain belongs to lineage I.

  • e The indicated MGEs are diverse among the lineages.

  • f The indicated type is defective with respect to mobility, i.e., does not carry mob genes.

  • g The indicated MGE was integrated into the chromosome within two strains.

  • h The indicated element was lost in some strains.