Skip to main content
  • ASM Journals
    • Antimicrobial Agents and Chemotherapy
    • Applied and Environmental Microbiology
    • Clinical Microbiology Reviews
    • Clinical and Vaccine Immunology
    • EcoSal Plus
    • Eukaryotic Cell
    • Infection and Immunity
    • Journal of Bacteriology
    • Journal of Clinical Microbiology
    • Journal of Microbiology & Biology Education
    • Journal of Virology
    • mBio
    • Microbiology and Molecular Biology Reviews
    • Microbiology Resource Announcements
    • Microbiology Spectrum
    • Molecular and Cellular Biology
    • mSphere
    • mSystems
  • Log in
  • My alerts
  • My Cart

Main menu

  • Home
  • Articles
    • Latest Articles
    • COVID-19 Research and News from ASM Journals
    • mSphere of Influence: Commentaries from Early Career Microbiologists
    • Archive
  • Topics
    • Applied and Environmental Science
    • Clinical Science and Epidemiology
    • Ecological and Evolutionary Science
    • Host-Microbe Biology
    • Molecular Biology and Physiology
    • Therapeutics and Prevention
  • For Authors
    • Getting Started
    • Submit a Manuscript
    • Scope
    • Editorial Policy
    • Submission, Review, & Publication Processes
    • Organization and Format
    • Errata, Author Corrections, Retractions
    • Illustrations and Tables
    • Nomenclature
    • Abbreviations and Conventions
    • Publication Fees
    • Ethics Resources and Policies
  • About the Journal
    • About mSphere
    • Editor in Chief
    • Board of Editors
    • For Reviewers
    • For the Media
    • For Librarians
    • For Advertisers
    • Alerts
    • RSS
    • FAQ
  • ASM Journals
    • Antimicrobial Agents and Chemotherapy
    • Applied and Environmental Microbiology
    • Clinical Microbiology Reviews
    • Clinical and Vaccine Immunology
    • EcoSal Plus
    • Eukaryotic Cell
    • Infection and Immunity
    • Journal of Bacteriology
    • Journal of Clinical Microbiology
    • Journal of Microbiology & Biology Education
    • Journal of Virology
    • mBio
    • Microbiology and Molecular Biology Reviews
    • Microbiology Resource Announcements
    • Microbiology Spectrum
    • Molecular and Cellular Biology
    • mSphere
    • mSystems

User menu

  • Log in
  • My alerts
  • My Cart

Search

  • Advanced search
mSphere
publisher-logosite-logo

Advanced Search

  • Home
  • Articles
    • Latest Articles
    • COVID-19 Research and News from ASM Journals
    • mSphere of Influence: Commentaries from Early Career Microbiologists
    • Archive
  • Topics
    • Applied and Environmental Science
    • Clinical Science and Epidemiology
    • Ecological and Evolutionary Science
    • Host-Microbe Biology
    • Molecular Biology and Physiology
    • Therapeutics and Prevention
  • For Authors
    • Getting Started
    • Submit a Manuscript
    • Scope
    • Editorial Policy
    • Submission, Review, & Publication Processes
    • Organization and Format
    • Errata, Author Corrections, Retractions
    • Illustrations and Tables
    • Nomenclature
    • Abbreviations and Conventions
    • Publication Fees
    • Ethics Resources and Policies
  • About the Journal
    • About mSphere
    • Editor in Chief
    • Board of Editors
    • For Reviewers
    • For the Media
    • For Librarians
    • For Advertisers
    • Alerts
    • RSS
    • FAQ

Archive

January/February 2021; Volume 6,Issue 1

Research Article

  • Identification of Nasal Gammaproteobacteria with Potent Activity against <span class="named-content genus-species" id="named-content-1">Staphylococcus aureus</span>: Novel Insights into the “Noncarrier” State
    Research Article | Host-Microbe Biology
    Identification of Nasal Gammaproteobacteria with Potent Activity against Staphylococcus aureus: Novel Insights into the “Noncarrier” State

    Nasal carriage of Staphylococcus aureus is a risk factor for infection, but it is not yet understood why some individuals carry nasal S. aureus persistently, intermittently, or seemingly not at all when tested via culture methods. This study compared the nasal microbiomes of established...

    Amy L. Cole, Meera Sundar, Ana Lopez, Anna Forsman, Shibu Yooseph, Alexander M. Cole
    6 Jan 2021
  • The Majority of Typhoid Toxin-Positive <em>Salmonella</em> Serovars Encode ArtB, an Alternate Binding Subunit
    Research Article | Host-Microbe Biology
    The Majority of Typhoid Toxin-Positive Salmonella Serovars Encode ArtB, an Alternate Binding Subunit

    While previous reports had suggested that the typhoid toxin (TT) could potentially use ArtB as an alternate binding subunit, this was thought to play a minor role in the evolution and biology of the toxin. In this study, we establish that both TT genes and artB are widespread among Salmonella enterica subsp. enterica, suggesting that TT likely plays...

    A. Gaballa, R. A. Cheng, A. S. Harrand, A. R. Cohn, M. Wiedmann
    6 Jan 2021
  • Coexpression of MmpS5 and MmpL5 Contributes to Both Efflux Transporter MmpL5 Trimerization and Drug Resistance in <span class="named-content genus-species" id="named-content-1">Mycobacterium tuberculosis</span>
    Research Article | Molecular Biology and Physiology
    Coexpression of MmpS5 and MmpL5 Contributes to Both Efflux Transporter MmpL5 Trimerization and Drug Resistance in Mycobacterium tuberculosis

    It has been reported that mycobacterial membrane protein large 5 (MmpL5), a resistance-nodulation-division (RND)-type inner membrane transporter in Mycobacterium tuberculosis (Mtb), is involved in the transport of antimycobacterial drugs. However, the functional roles of the membrane fusion protein mycobacterial membrane protein small 5 (MmpS5), organized as...

    Kentaro Yamamoto, Noboru Nakata, Tetsu Mukai, Ikuro Kawagishi, Manabu Ato
    6 Jan 2021
  • <span class="named-content genus-species" id="named-content-1">Escherichia coli</span> Genomic Diversity within Extraintestinal Acute Infections Argues for Adaptive Evolution at Play
    Research Article | Ecological and Evolutionary Science
    Escherichia coli Genomic Diversity within Extraintestinal Acute Infections Argues for Adaptive Evolution at Play

    Little is known about the dynamics of adaptation in acute bacterial infections. By sequencing multiple isolates from monoclonal extraintestinal Escherichia coli infections in several patients, we were able to uncover traces of selection taking place at short time scales compared to chronic infection.

    Antoine Bridier-Nahmias, Adrien Launay, Alexandre Bleibtreu, Mélanie Magnan, Violaine Walewski, Jérémie Chatel, Sara Dion, Véronique Robbe-Saule, Olivier Clermont, Françoise Norel, Erick Denamur, Olivier Tenaillon
    6 Jan 2021
  • Disentangling the Relative Roles of Vertical Transmission, Subsequent Colonizations, and Diet on Cockroach Microbiome Assembly
    Research Article | Host-Microbe Biology
    Disentangling the Relative Roles of Vertical Transmission, Subsequent Colonizations, and Diet on Cockroach Microbiome Assembly

    When host fitness is dependent on gut microbiota, microbial community flexibility and reproducibility enhance host fitness by allowing fine-tuned environmental tracking and sufficient stability for host traits to evolve. Our findings lend support to the importance of vertically transmitted early-life microbiota as stabilizers through interactions with potential colonizers that may contribute to ensuring that the microbiota aligns within...

    Justinn Renelies-Hamilton, Kristjan Germer, David Sillam-Dussès, Kasun H. Bodawatta, Michael Poulsen
    6 Jan 2021
  • Small RNAs Are Implicated in Regulation of Gene and Transposable Element Expression in the Protist <span class="named-content genus-species" id="named-content-1">Trichomonas vaginalis</span>
    Research Article | Host-Microbe Biology
    Small RNAs Are Implicated in Regulation of Gene and Transposable Element Expression in the Protist Trichomonas vaginalis

    Trichomoniasis, caused by the protozoan Trichomonas vaginalis, is the most common nonviral sexually transmitted infection in humans. The millions of cases each year have sequelae that may include complications during pregnancy and increased risk of HIV infection.

    Sally D. Warring, Frances Blow, Grace Avecilla, Jordan C. Orosco, Steven A. Sullivan, Jane M. Carlton
    6 Jan 2021
  • Human Cytomegalovirus UL7, miR-US5-1, and miR-UL112-3p Inactivation of FOXO3a Protects CD34<sup>+</sup> Hematopoietic Progenitor Cells from Apoptosis
    Research Article | Host-Microbe Biology
    Human Cytomegalovirus UL7, miR-US5-1, and miR-UL112-3p Inactivation of FOXO3a Protects CD34+ Hematopoietic Progenitor Cells from Apoptosis

    Human cytomegalovirus (HCMV) causes serious disease in immunocompromised individuals and is a significant problem during transplantation. The virus can establish a latent infection in CD34+ hematopoietic progenitor cells (HPCs) and periodically reactivate to cause disease in the absence of an intact immune system.

    Meaghan H. Hancock, Lindsey B. Crawford, Wilma Perez, Hillary M. Struthers, Jennifer Mitchell, Patrizia Caposio
    6 Jan 2021
  • Structure-Guided Design of a Synthetic Mimic of an Endothelial Protein C Receptor-Binding PfEMP1 Protein
    Research Article | Host-Microbe Biology
    Structure-Guided Design of a Synthetic Mimic of an Endothelial Protein C Receptor-Binding PfEMP1 Protein

    Vaccines train our immune systems to generate antibodies which recognize pathogens. Some of these antibodies are highly protective, preventing infection, while others are ineffective.

    Natalie M. Barber, Clinton K. Y. Lau, Louise Turner, Gareth Watson, Susan Thrane, John P. A. Lusingu, Thomas Lavstsen, Matthew K. Higgins
    6 Jan 2021
  • Next-Generation Sequencing Analysis of the Within-Host Genetic Diversity of Influenza A(H1N1)pdm09 Viruses in the Upper and Lower Respiratory Tracts of Patients with Severe Influenza
    Research Article | Clinical Science and Epidemiology
    Next-Generation Sequencing Analysis of the Within-Host Genetic Diversity of Influenza A(H1N1)pdm09 Viruses in the Upper and Lower Respiratory Tracts of Patients with Severe Influenza

    The D222G/N substitution in the hemagglutinin (HA) protein of influenza A(H1N1)pdm09 virus has been reported to be associated with disease severity and mortality in numerous previous studies. In the present study, 75% of lower respiratory samples contained heterogeneous influenza populations that carried different amino acids at position 222 of the HA protein, whereas all upper respiratory samples only contained the wild-type 222D....

    Ikuyo Takayama, Binh Gia Nguyen, Co Xuan Dao, Thach The Pham, Tuan Quoc Dang, Phuong Thai Truong, Thanh Van Do, Thuy Thi Phuong Pham, Seiichiro Fujisaki, Takato Odagiri, Hideki Hasegawa, Noriko Nakajima
    6 Jan 2021
  • Genomic Epidemiology and Evolution of <em>Escherichia coli</em> in Wild Animals in Mexico
    Research Article | Host-Microbe Biology
    Genomic Epidemiology and Evolution of Escherichia coli in Wild Animals in Mexico

    Escherichia coli is a clinically important bacterial species implicated in human- and livestock-associated infections worldwide. The bacterium is known to reside in the guts of humans, livestock, and wild animals.

    Robert Murphy, Martin Palm, Ville Mustonen, Jonas Warringer, Anne Farewell, Leopold Parts, Danesh Moradigaravand
    6 Jan 2021
  • Dichloroacetate and Pyruvate Metabolism: Pyruvate Dehydrogenase Kinases as Targets Worth Investigating for Effective Therapy of Toxoplasmosis
    Research Article | Therapeutics and Prevention
    Dichloroacetate and Pyruvate Metabolism: Pyruvate Dehydrogenase Kinases as Targets Worth Investigating for Effective Therapy of Toxoplasmosis

    Currently, the drugs used for toxoplasmosis have severe toxicity to human cells, and the treatment still lacks effective and safer alternatives. The search for novel drug targets is timely.

    Mariana Galvão Ferrarini, Lindice Mitie Nisimura, Richard Marcel Bruno Moreira Girard, Mayke Bezerra Alencar, Mariana Sayuri Ishikawa Fragoso, Carlla Assis Araújo-Silva, Alan de Almeida Veiga, Ana Paula Ressetti Abud, Sheila Cristina Nardelli, Rossiane C. Vommaro, Ariel Mariano Silber, Marie France-Sagot, Andréa Rodrigues Ávila
    6 Jan 2021
  • Monitoring COVID-19 Transmission Risks by Quantitative Real-Time PCR Tracing of Droplets in Hospital and Living Environments
    Research Article | Clinical Science and Epidemiology
    Monitoring COVID-19 Transmission Risks by Quantitative Real-Time PCR Tracing of Droplets in Hospital and Living Environments

    Several studies evaluated the presence of SARS-CoV-2 in the environment. Saliva and nasopharyngeal droplets can land on objects and surfaces, creating fomites.

    Andrea Piana, Maria Eugenia Colucci, Federica Valeriani, Adriano Marcolongo, Giovanni Sotgiu, Cesira Pasquarella, Lory Marika Margarucci, Andrea Petrucca, Gianluca Gianfranceschi, Sergio Babudieri, Pietro Vitali, Giuseppe D’Ermo, Assunta Bizzarro, Flavio De Maio, Matteo Vitali, Antonio Azara, Ferdinando Romano, Maurizio Simmaco, Vincenzo Romano Spica
    6 Jan 2021
  • Association of Zinc Finger Antiviral Protein Binding to Viral Genomic RNA with Attenuation of Replication of Echovirus 7
    Research Article | Host-Microbe Biology
    Association of Zinc Finger Antiviral Protein Binding to Viral Genomic RNA with Attenuation of Replication of Echovirus 7

    We recently discovered that the OAS3/RNase L antiviral pathway is essential for restriction of CpG- and UpA-enriched viruses, in addition to the requirement for zinc finger antiviral protein (ZAP). The current study provides evidence for the specific dinucleotide and wider recognition contexts associated with virus recognition and attenuation.

    Niluka Goonawardane, Dung Nguyen, Peter Simmonds
    6 Jan 2021
  • Analysis of Apoptosis-Related Genes Reveals that Apoptosis Functions in Conidiation and Pathogenesis of <em>Fusarium pseudograminearum</em>
    Research Article | Host-Microbe Biology
    Analysis of Apoptosis-Related Genes Reveals that Apoptosis Functions in Conidiation and Pathogenesis of Fusarium pseudograminearum

    The plant-pathogenic fungus F. pseudograminearum is the causal agent of Fusarium crown rot (FCR) in wheat and barley, resulting in substantial yield losses worldwide. Particularly, in the Huanghuai wheat-growing region of China, F. pseudograminearum was reported as the dominant Fusarium species in FCR infections.

    Linlin Chen, Yuming Ma, Mengya Peng, Wenbo Chen, Huiqing Xia, Jingya Zhao, Yake Zhang, Zhuo Fan, Xiaoping Xing, Honglian Li
    6 Jan 2021
  • Novel Immune Modulators Enhance <em>Caenorhabditis elegans</em> Resistance to Multiple Pathogens
    Research Article | Host-Microbe Biology
    Novel Immune Modulators Enhance Caenorhabditis elegans Resistance to Multiple Pathogens

    Trends moving in opposite directions (increasing antimicrobial resistance and declining novel antimicrobial development) have precipitated a looming crisis: a nearly complete inability to safely and effectively treat bacterial infections. To avert this, new approaches are needed.

    Nicholas A. Hummell, Alexey V. Revtovich, Natalia V. Kirienko
    6 Jan 2021
  • Amplicon Sequencing-Based Bipartite Network Analysis Confirms a High Degree of Specialization and Modularity for Fungi and Prokaryotes in Deadwood
    Research Article | Applied and Environmental Science
    Amplicon Sequencing-Based Bipartite Network Analysis Confirms a High Degree of Specialization and Modularity for Fungi and Prokaryotes in Deadwood

    Deadwood is important for our forest ecosystems. It feeds and houses many organisms, e.g., fungi and prokaryotes, with many different species contributing to its decomposition and nutrient cycling.

    Julia Moll, Anna Heintz-Buschart, Claus Bässler, Martin Hofrichter, Harald Kellner, François Buscot, Björn Hoppe
    13 Jan 2021
  • <span class="named-content genus-species" id="named-content-1">Staphylococcus aureus</span> Tolerance and Genomic Response to Photodynamic Inactivation
    Research Article | Therapeutics and Prevention
    Staphylococcus aureus Tolerance and Genomic Response to Photodynamic Inactivation

    Staphylococcus aureus can cause disease at most body sites, with illness ranging from asymptomatic infection to death. The increasing prevalence of antibiotic-resistant strains results in treatment failures and high mortality rates. S. aureus acquires resistance to antibiotics through multiple...

    Sara B. Snell, Ann Lindley Gill, Constantine G. Haidaris, Thomas H. Foster, Timothy M. Baran, Steven R. Gill
    6 Jan 2021
  • Phosphorylation of the Canonical Histone H2A Marks Foci of Damaged DNA in Malaria Parasites
    Research Article | Molecular Biology and Physiology
    Phosphorylation of the Canonical Histone H2A Marks Foci of Damaged DNA in Malaria Parasites

    Plasmodium falciparum is the deadliest human parasite that causes malaria when it reaches the bloodstream and begins proliferating inside red blood cells, where the parasites are particularly prone to DNA damage. The molecular mechanisms that allow these pathogens to maintain their genome integrity under such conditions are also the driving force for acquiring genome...

    Manish Goyal, Adina Heinberg, Vera Mitesser, Sofiya Kandelis-Shalev, Brajesh Kumar Singh, Ron Dzikowski
    13 Jan 2021
  • Randomized Controlled Trial of Oral Vancomycin Treatment in <span class="named-content genus-species" id="named-content-1">Clostridioides difficile</span>-Colonized Patients
    Editor's Pick Research Article | Host-Microbe Biology
    Randomized Controlled Trial of Oral Vancomycin Treatment in Clostridioides difficile-Colonized Patients

    A gold standard diagnostic for Clostridioides difficile infection (CDI) does not exist. An area of controversy is how to manage patients whose stool tests positive by nucleic acid amplification tests but negative by toxin enzyme immunoassay.

    Skye R. S. Fishbein, Tiffany Hink, Kimberly A. Reske, Candice Cass, Emily Struttmann, Zainab Hassan Iqbal, Sondra Seiler, Jennie H. Kwon, Carey-Ann D. Burnham, Gautam Dantas, Erik R. Dubberke
    13 Jan 2021
  • Genes Influencing Phage Host Range in <span class="named-content genus-species" id="named-content-1">Staphylococcus aureus</span> on a Species-Wide Scale
    Research Article | Ecological and Evolutionary Science
    Genes Influencing Phage Host Range in Staphylococcus aureus on a Species-Wide Scale

    Staphylococcus aureus is a widespread, hospital- and community-acquired pathogen, many strains of which are antibiotic resistant. It causes diverse diseases, ranging from local to systemic infection, and affects both the skin and many internal organs, including the heart, lungs, bones, and brain.

    Abraham G. Moller, Kyle Winston, Shiyu Ji, Junting Wang, Michelle N. Hargita Davis, Claudia R. Solís-Lemus, Timothy D. Read
    13 Jan 2021
  • Coexistence of Communicating and Noncommunicating Cells in the Filamentous Cyanobacterium <em>Anabaena</em>
    Research Article | Molecular Biology and Physiology
    Coexistence of Communicating and Noncommunicating Cells in the Filamentous Cyanobacterium Anabaena

    Multicellularity is found in bacteria as well as in eukaryotes, and the filamentous heterocyst-forming (N2-fixing) cyanobacteria represent a simple and ancient paradigm of multicellular organisms. Multicellularity generally involves cell-cell adhesion and communication.

    Sergio Arévalo, Anja Nenninger, Mercedes Nieves-Morión, Antonia Herrero, Conrad W. Mullineaux, Enrique Flores
    13 Jan 2021
  • Soil Health Management Enhances Microbial Nitrogen Cycling Capacity and Activity
    Research Article | Applied and Environmental Science
    Soil Health Management Enhances Microbial Nitrogen Cycling Capacity and Activity

    Conservation agriculture practices that promote soil health have distinct and lasting effects on microbial populations involved with soil nitrogen (N) cycling. In particular, using a leguminous winter cover crop (hairy vetch) promoted the expression of key functional genes involved in soil N cycling, equaling or exceeding the effects of inorganic N fertilizer.

    Jialin Hu, Virginia L. Jin, Julie Y. M. Konkel, Sean M. Schaeffer, Liesel G. Schneider, Jennifer M. DeBruyn
    13 Jan 2021
  • A Novel N4-Like Bacteriophage Isolated from a Wastewater Source in South India with Activity against Several Multidrug-Resistant Clinical <span class="named-content genus-species" id="named-content-1">Pseudomonas aeruginosa</span> Isolates
    Research Article | Clinical Science and Epidemiology
    A Novel N4-Like Bacteriophage Isolated from a Wastewater Source in South India with Activity against Several Multidrug-Resistant Clinical Pseudomonas aeruginosa Isolates

    In India, multidrug resistance determinants are much more abundant in community-associated bacterial pathogens due to the improper treatment of domestic and industrial effluents. In particular, a high bacterial load of the opportunistic pathogen P. aeruginosa in sewage and water bodies in India is well documented.

    Nitasha D. Menon, Megha S. Kumar, T. G. Satheesh Babu, Sucharita Bose, Gayathri Vijayakumar, Manasi Baswe, Meghna Chatterjee, Jovita Rowena D’Silva, Kavya Shetty, Jayalekshmi Haripriyan, Anil Kumar, Samitha Nair, Priyanka Somanath, Bipin G. Nair, Victor Nizet, Geetha B. Kumar
    13 Jan 2021
  • Specific Norovirus Interaction with Lewis x and Lewis a on Human Intestinal Inflammatory Mucosa during Refractory Inflammatory Bowel Disease
    Research Article | Host-Microbe Biology
    Specific Norovirus Interaction with Lewis x and Lewis a on Human Intestinal Inflammatory Mucosa during Refractory Inflammatory Bowel Disease

    Inflammatory bowel disease (IBD), including Crohn’s disease (CD) and ulcerative colitis (UC), are progressive diseases affecting millions of people each year. Flare-ups during IBD result in severe mucosal alterations of the small intestine (in CD) and in the colon and rectum (in CD and UC).

    Georges Tarris, Alexis de Rougemont, Marie Estienney, Maeva Charkaoui, Thomas Mouillot, Bernard Bonnotte, Christophe Michiels, Laurent Martin, Gaël Belliot
    13 Jan 2021
  • OXA-181-Like Carbapenemases in <span class="named-content genus-species" id="named-content-1">Klebsiella pneumoniae</span> ST14, ST15, ST23, ST48, and ST231 from Septicemic Neonates: Coexistence with NDM-5, Resistome, Transmissibility, and Genome Diversity
    Research Article | Clinical Science and Epidemiology
    OXA-181-Like Carbapenemases in Klebsiella pneumoniae ST14, ST15, ST23, ST48, and ST231 from Septicemic Neonates: Coexistence with NDM-5, Resistome, Transmissibility, and Genome Diversity

    Neonatal sepsis is a leading cause of neonatal mortality in low- and middle-income countries (LMICs). Treatment of sepsis in this vulnerable population is dependent on antimicrobials, and resistance to these life-saving antimicrobials is worrisome.

    Sharmi Naha, Kirsty Sands, Subhankar Mukherjee, Bijan Saha, Shanta Dutta, Sulagna Basu
    13 Jan 2021

Commentary

  • mSphere of Influence: Turning to Soil for Medicines
    Commentary | Therapeutics and Prevention
    mSphere of Influence: Turning to Soil for Medicines

    Ching-Hsuan Lin works in the field of Candida biology. In this mSphere of Influence article, he reflects on how the papers “Use of ichip for high-throughput in situ cultivation of uncultivable microbial species” by D.

    Ching-Hsuan Lin
    6 Jan 2021
  • mSphere of Influence: the Complexity of Interferon Gamma-Mediated Pathogen Control
    Commentary | Host-Microbe Biology
    mSphere of Influence: the Complexity of Interferon Gamma-Mediated Pathogen Control

    Bryan D. Bryson works in the field of biological engineering with a specific interest in host-mycobacterium interactions.

    Bryan D. Bryson
    6 Jan 2021
  • Uncovering the Harms of Treating <span class="named-content genus-species" id="named-content-1">Clostridioides difficile</span> Colonization
    Commentary | Therapeutics and Prevention
    Uncovering the Harms of Treating Clostridioides difficile Colonization

    Patients with toxin-negative Clostridioides difficile-positive diarrhea are often treated with oral vancomycin with the assumption that treatment is more beneficial than harmful. However, this hypothesis has never been formally tested, and recent studies suggest that most such patients recover quickly without treatment and can be colonized rather than infected.

    ...
    Christopher R. Polage, Nicholas A. Turner
    13 Jan 2021

Observation

  • An Observational Laboratory-Based Assessment of SARS-CoV-2 Molecular Diagnostics in Benin, Western Africa
    Observation | Clinical Science and Epidemiology
    An Observational Laboratory-Based Assessment of SARS-CoV-2 Molecular Diagnostics in Benin, Western Africa

    Months after the start of the COVID-19 pandemic, case numbers from Africa are surprisingly low, potentially because the number of SARS-CoV-2 tests performed in Africa is lower than in other regions. Here, we show an overload of COVID-19-related diagnostics in the central laboratory of Benin, Western Africa, with a stagnating average number of positive samples irrespective of daily sample counts.

    Anna-Lena Sander, Anges Yadouleton, Andres Moreira-Soto, Carine Tchibozo, Gildas Hounkanrin, Yvette Badou, Carlo Fischer, Nina Krause, Petas Akogbeto, Edmilson F. de Oliveira Filho, Anges Dossou, Sebastian Brünink, Christian Drosten, Melchior A. Joël Aïssi, Mamoudou Harouna Djingarey, Benjamin Hounkpatin, Michael Nagel, Jan Felix Drexler
    13 Jan 2021
Previous
Back to top

In This Issue

volume 6, issue 1
Sign up for alerts

Jump to

  • Research Article
  • Commentary
  • Observation
  • Most Read
  • Most Cited
Loading
  • Effectiveness of Face Masks in Preventing Airborne Transmission of SARS-CoV-2
  • Conserved Genomic Terminals of SARS-CoV-2 as Coevolving Functional Elements and Potential Therapeutic Targets
  • COVID-19 Hyperinflammation: What about Neutrophils?
  • Rampant C→U Hypermutation in the Genomes of SARS-CoV-2 and Other Coronaviruses: Causes and Consequences for Their Short- and Long-Term Evolutionary Trajectories
More...

About

  • About mSphere
  • Board of Editors
  • Policies
  • For Reviewers
  • For the Media
  • Embargo Policy
  • For Librarians
  • For Advertisers
  • Alerts
  • RSS
  • FAQ
  • Permissions
  • Journal Announcements

Authors

  • ASM Author Center
  • Submit a Manuscript
  • Author Warranty
  • Types of Articles
  • Getting Started
  • Ethics
  • Contact Us

Follow #mSphereJ

@ASMicrobiology

       

 

Website feedback

ASM Journals

ASM journals are the most prominent publications in the field, delivering up-to-date and authoritative coverage of both basic and clinical microbiology.

About ASM | Contact Us | Press Room

 

ASM is a member of

Scientific Society Publisher Alliance

 

American Society for Microbiology
1752 N St. NW
Washington, DC 20036
Phone: (202) 737-3600

Copyright © 2021 American Society for Microbiology | Privacy Policy | Website feedback

Online ISSN: 2379-5042