Research Article | Molecular Biology and Physiology

The Two-Component System CopRS Maintains Subfemtomolar Levels of Free Copper in the Periplasm of Pseudomonas aeruginosa Using a Phosphatase-Based Mechanism

Lorena Novoa-Aponte, Cheng Xu, Fernando C. Soncini, José M. Argüello
Craig D. Ellermeier, Editor
DOI: 10.1128/mSphere.01193-20

Article Information

DOI 
https://doi.org/10.1128/mSphere.01193-20
PubMed 
33361129
Published By 
American Society for Microbiology Journals
History 
  • Received November 24, 2020
  • Accepted November 27, 2020
  • Published online December 23, 2020.
Copyright & Usage 
Copyright © 2020 Novoa-Aponte et al. This is an open-access article distributed under the terms of the Creative Commons Attribution 4.0 International license.
Editors and / or Reviewers 
  • Craig D. Ellermeier, Editor, University of Iowa

Author Information

  1. Lorena Novoa-Apontea,
  2. Cheng Xua,
  3. Fernando C. Soncinib and
  4. José M. Argüelloa
  1. aDepartment of Chemistry and Biochemistry, Worcester Polytechnic Institute, Worcester, Massachusetts, USA
  2. bInstituto de Biología Molecular y Celular de Rosario, Universidad Nacional de Rosario, Consejo Nacional de Investigaciones Científicas y Técnicas, Rosario, Santa Fe, Argentina
  • Address correspondence to José M. Argüello, arguello{at}wpi.edu.

  • Citation Novoa-Aponte L, Xu C, Soncini FC, Argüello JM. 2020. The two-component system CopRS maintains subfemtomolar levels of free copper in the periplasm of Pseudomonas aeruginosa using a phosphatase-based mechanism. mSphere 5:e01193-20. https://doi.org/10.1128/mSphere.01193-20.

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Article usage: December 2020 to February 2021

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KEYWORDS

Pseudomonas aeruginosa
copper
homeostasis
periplasm
two-component regulatory systems

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