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Research Article | Therapeutics and Prevention

Oxalate-Degrading Bacillus subtilis Mitigates Urolithiasis in a Drosophila melanogaster Model

Kait F. Al, Brendan A. Daisley, Ryan M. Chanyi, Jennifer Bjazevic, Hassan Razvi, Gregor Reid, Jeremy P. Burton
Maria L. Marco, Editor
Kait F. Al
aCanadian Centre for Human Microbiome and Probiotic Research, Lawson Health Research Institute, London, Ontario, Canada
bDepartment of Microbiology and Immunology, Western University, London, Ontario, Canada
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Brendan A. Daisley
aCanadian Centre for Human Microbiome and Probiotic Research, Lawson Health Research Institute, London, Ontario, Canada
bDepartment of Microbiology and Immunology, Western University, London, Ontario, Canada
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  • ORCID record for Brendan A. Daisley
Ryan M. Chanyi
aCanadian Centre for Human Microbiome and Probiotic Research, Lawson Health Research Institute, London, Ontario, Canada
bDepartment of Microbiology and Immunology, Western University, London, Ontario, Canada
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Jennifer Bjazevic
cDivision of Urology, Department of Surgery, Western University, London, Ontario, Canada
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Hassan Razvi
cDivision of Urology, Department of Surgery, Western University, London, Ontario, Canada
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Gregor Reid
aCanadian Centre for Human Microbiome and Probiotic Research, Lawson Health Research Institute, London, Ontario, Canada
bDepartment of Microbiology and Immunology, Western University, London, Ontario, Canada
cDivision of Urology, Department of Surgery, Western University, London, Ontario, Canada
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Jeremy P. Burton
aCanadian Centre for Human Microbiome and Probiotic Research, Lawson Health Research Institute, London, Ontario, Canada
bDepartment of Microbiology and Immunology, Western University, London, Ontario, Canada
cDivision of Urology, Department of Surgery, Western University, London, Ontario, Canada
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Maria L. Marco
University of California, Davis
Roles: Editor
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DOI: 10.1128/mSphere.00498-20
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Article Information

DOI 
https://doi.org/10.1128/mSphere.00498-20
PubMed 
32907948

Published By 
American Society for Microbiology Journals
History 
  • Received May 26, 2020
  • Accepted August 27, 2020
  • Published online September 9, 2020.

Copyright & Usage 
Copyright © 2020 Al et al. This is an open-access article distributed under the terms of the Creative Commons Attribution 4.0 International license.
Editors and / or Reviewers 
  • Maria L. Marco, Editor, University of California, Davis

Author Information

  1. Kait F. Ala,b,
  2. Brendan A. Daisleya,b,
  3. Ryan M. Chanyia,b*,
  4. Jennifer Bjazevicc,
  5. Hassan Razvic,
  6. Gregor Reida,b,c and
  7. Jeremy P. Burtona,b,c
  1. aCanadian Centre for Human Microbiome and Probiotic Research, Lawson Health Research Institute, London, Ontario, Canada
  2. bDepartment of Microbiology and Immunology, Western University, London, Ontario, Canada
  3. cDivision of Urology, Department of Surgery, Western University, London, Ontario, Canada
  • Address correspondence to Jeremy P. Burton, Jeremy.Burton{at}lawsonresearch.com.
  • ↵* Present address: Ryan M. Chanyi, AgResearch Ltd., Food & Bio-based Products, Grasslands Research Centre, Palmerston North, New Zealand.

  • Citation Al KF, Daisley BA, Chanyi RM, Bjazevic J, Razvi H, Reid G, Burton JP. 2020. Oxalate-degrading Bacillus subtilis mitigates urolithiasis in a Drosophila melanogaster model. mSphere 5:e00498-20. https://doi.org/10.1128/mSphere.00498-20.

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Oxalate-Degrading Bacillus subtilis Mitigates Urolithiasis in a Drosophila melanogaster Model
Kait F. Al, Brendan A. Daisley, Ryan M. Chanyi, Jennifer Bjazevic, Hassan Razvi, Gregor Reid, Jeremy P. Burton
mSphere Sep 2020, 5 (5) e00498-20; DOI: 10.1128/mSphere.00498-20

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Oxalate-Degrading Bacillus subtilis Mitigates Urolithiasis in a Drosophila melanogaster Model
Kait F. Al, Brendan A. Daisley, Ryan M. Chanyi, Jennifer Bjazevic, Hassan Razvi, Gregor Reid, Jeremy P. Burton
mSphere Sep 2020, 5 (5) e00498-20; DOI: 10.1128/mSphere.00498-20
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KEYWORDS

Bacillus subtilis
Drosophila
calcium oxalate
host-microbe interactions
microbiota
nephrolithiasis
Probiotics

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