Oxalate-Degrading Bacillus subtilis Mitigates Urolithiasis in a Drosophila melanogaster Model

Kait F. Al; Brendan A. Daisley; Ryan M. Chanyi; Jennifer Bjazevic; Hassan Razvi; Gregor Reid; Jeremy P. Burton

doi:10.1128/mSphere.00498-20

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Research Article | Therapeutics and Prevention

Oxalate-Degrading Bacillus subtilis Mitigates Urolithiasis in a Drosophila melanogaster Model

Kait F. Al, Brendan A. Daisley, Ryan M. Chanyi, Jennifer Bjazevic, Hassan Razvi, Gregor Reid, Jeremy P. Burton

Maria L. Marco, Editor

Kait F. Al

aCanadian Centre for Human Microbiome and Probiotic Research, Lawson Health Research Institute, London, Ontario, Canada

bDepartment of Microbiology and Immunology, Western University, London, Ontario, Canada

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Brendan A. Daisley

aCanadian Centre for Human Microbiome and Probiotic Research, Lawson Health Research Institute, London, Ontario, Canada

bDepartment of Microbiology and Immunology, Western University, London, Ontario, Canada

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ORCID record for Brendan A. Daisley

Ryan M. Chanyi

aCanadian Centre for Human Microbiome and Probiotic Research, Lawson Health Research Institute, London, Ontario, Canada

bDepartment of Microbiology and Immunology, Western University, London, Ontario, Canada

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Jennifer Bjazevic

cDivision of Urology, Department of Surgery, Western University, London, Ontario, Canada

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Hassan Razvi

cDivision of Urology, Department of Surgery, Western University, London, Ontario, Canada

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Gregor Reid

aCanadian Centre for Human Microbiome and Probiotic Research, Lawson Health Research Institute, London, Ontario, Canada

bDepartment of Microbiology and Immunology, Western University, London, Ontario, Canada

cDivision of Urology, Department of Surgery, Western University, London, Ontario, Canada

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ORCID record for Gregor Reid

Jeremy P. Burton

aCanadian Centre for Human Microbiome and Probiotic Research, Lawson Health Research Institute, London, Ontario, Canada

bDepartment of Microbiology and Immunology, Western University, London, Ontario, Canada

cDivision of Urology, Department of Surgery, Western University, London, Ontario, Canada

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ORCID record for Jeremy P. Burton

Maria L. Marco

University of California, Davis

Roles: Editor

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DOI: 10.1128/mSphere.00498-20

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DOI

https://doi.org/10.1128/mSphere.00498-20

PubMed

32907948

Published By

American Society for Microbiology Journals

History

Received May 26, 2020
Accepted August 27, 2020
Published online September 9, 2020.

Editors and / or Reviewers

Maria L. Marco, Editor, University of California, Davis

Author Information

Kait F. Al^a,^b,
Brendan A. Daisley^a,^b,
Ryan M. Chanyi^a,^b *,
Jennifer Bjazevic^c,
Hassan Razvi^c,
Gregor Reid^a,^b,^c and
Jeremy P. Burton^a,^b,^c

^aCanadian Centre for Human Microbiome and Probiotic Research, Lawson Health Research Institute, London, Ontario, Canada
^bDepartment of Microbiology and Immunology, Western University, London, Ontario, Canada
^cDivision of Urology, Department of Surgery, Western University, London, Ontario, Canada

Address correspondence to Jeremy P. Burton, Jeremy.Burton{at}lawsonresearch.com.
↵* Present address: Ryan M. Chanyi, AgResearch Ltd., Food & Bio-based Products, Grasslands Research Centre, Palmerston North, New Zealand.
Citation Al KF, Daisley BA, Chanyi RM, Bjazevic J, Razvi H, Reid G, Burton JP. 2020. Oxalate-degrading Bacillus subtilis mitigates urolithiasis in a Drosophila melanogaster model. mSphere 5:e00498-20. https://doi.org/10.1128/mSphere.00498-20.

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Oct 2020	43	163	116
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Dec 2020	17	79	31
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Oxalate-Degrading Bacillus subtilis Mitigates Urolithiasis in a Drosophila melanogaster Model

Kait F. Al, Brendan A. Daisley, Ryan M. Chanyi, Jennifer Bjazevic, Hassan Razvi, Gregor Reid, Jeremy P. Burton

mSphere Sep 2020, 5 (5) e00498-20; DOI: 10.1128/mSphere.00498-20

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Oxalate-Degrading Bacillus subtilis Mitigates Urolithiasis in a Drosophila melanogaster Model

Kait F. Al, Brendan A. Daisley, Ryan M. Chanyi, Jennifer Bjazevic, Hassan Razvi, Gregor Reid, Jeremy P. Burton

mSphere Sep 2020, 5 (5) e00498-20; DOI: 10.1128/mSphere.00498-20

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KEYWORDS

Bacillus subtilis

Drosophila

calcium oxalate

host-microbe interactions

microbiota

nephrolithiasis

Probiotics

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Oxalate-Degrading Bacillus subtilis Mitigates Urolithiasis in a Drosophila melanogaster Model

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