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Editor's Pick Research Article | Host-Microbe Biology

Distinct Fecal and Plasma Metabolites in Children with Autism Spectrum Disorders and Their Modulation after Microbiota Transfer Therapy

Dae-Wook Kang, James B. Adams, Troy Vargason, Marina Santiago, Juergen Hahn, Rosa Krajmalnik-Brown
Maria L. Marco, Editor
Dae-Wook Kang
aBiodesign Swette Center for Environmental Biotechnology, Arizona State University, Tempe, Arizona, USA
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  • ORCID record for Dae-Wook Kang
James B. Adams
bSchool for Engineering of Matter, Transport and Energy, Arizona State University, Tempe, Arizona, USA
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Troy Vargason
cDepartment of Biomedical Engineering, Rensselaer Polytechnic Institute, Troy, New York, USA
dCenter for Biotechnology and Interdisciplinary Studies, Rensselaer Polytechnic Institute, Troy, New York, USA
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Marina Santiago
eFinch Therapeutics, Somerville, Massachusetts, USA
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Juergen Hahn
cDepartment of Biomedical Engineering, Rensselaer Polytechnic Institute, Troy, New York, USA
dCenter for Biotechnology and Interdisciplinary Studies, Rensselaer Polytechnic Institute, Troy, New York, USA
fDepartment of Chemical and Biological Engineering, Rensselaer Polytechnic Institute, Troy, New York, USA
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Rosa Krajmalnik-Brown
aBiodesign Swette Center for Environmental Biotechnology, Arizona State University, Tempe, Arizona, USA
gSchool of Sustainable Engineering and the Built Environment, Arizona State University, Tempe, Arizona, USA
hBiodesign Center for Health Through Microbiomes, Arizona State University, Tempe, Arizona, USA
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Maria L. Marco
University of California, Davis
Roles: Editor
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DOI: 10.1128/mSphere.00314-20
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Article Information

DOI 
https://doi.org/10.1128/mSphere.00314-20
PubMed 
33087514

Published By 
American Society for Microbiology Journals
History 
  • Received April 9, 2020
  • Accepted September 20, 2020
  • Published online October 21, 2020.

Copyright & Usage 
Copyright © 2020 Kang et al. This is an open-access article distributed under the terms of the Creative Commons Attribution 4.0 International license.
Editors and / or Reviewers 
  • Maria L. Marco, Editor, University of California, Davis

Author Information

  1. Dae-Wook Kanga*,
  2. James B. Adamsb,
  3. Troy Vargasonc,d,
  4. Marina Santiagoe,
  5. Juergen Hahnc,d,f and
  6. Rosa Krajmalnik-Browna,g,h
  1. aBiodesign Swette Center for Environmental Biotechnology, Arizona State University, Tempe, Arizona, USA
  2. bSchool for Engineering of Matter, Transport and Energy, Arizona State University, Tempe, Arizona, USA
  3. cDepartment of Biomedical Engineering, Rensselaer Polytechnic Institute, Troy, New York, USA
  4. dCenter for Biotechnology and Interdisciplinary Studies, Rensselaer Polytechnic Institute, Troy, New York, USA
  5. eFinch Therapeutics, Somerville, Massachusetts, USA
  6. fDepartment of Chemical and Biological Engineering, Rensselaer Polytechnic Institute, Troy, New York, USA
  7. gSchool of Sustainable Engineering and the Built Environment, Arizona State University, Tempe, Arizona, USA
  8. hBiodesign Center for Health Through Microbiomes, Arizona State University, Tempe, Arizona, USA
  • Address correspondence to Dae-Wook Kang, daewook.kang{at}utoledo.edu, or Rosa Krajmalnik-Brown, Dr.Rosy{at}asu.edu.
  • ↵* Present address: Dae-Wook Kang, Department of Civil and Environmental Engineering, The University of Toledo, Toledo, Ohio, USA.

  • Citation Kang D-W, Adams JB, Vargason T, Santiago M, Hahn J, Krajmalnik-Brown R. 2020. Distinct fecal and plasma metabolites in children with autism spectrum disorders and their modulation after microbiota transfer therapy. mSphere 5:e00314-20. https://doi.org/10.1128/mSphere.00314-20.

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Distinct Fecal and Plasma Metabolites in Children with Autism Spectrum Disorders and Their Modulation after Microbiota Transfer Therapy
Dae-Wook Kang, James B. Adams, Troy Vargason, Marina Santiago, Juergen Hahn, Rosa Krajmalnik-Brown
mSphere Oct 2020, 5 (5) e00314-20; DOI: 10.1128/mSphere.00314-20

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Distinct Fecal and Plasma Metabolites in Children with Autism Spectrum Disorders and Their Modulation after Microbiota Transfer Therapy
Dae-Wook Kang, James B. Adams, Troy Vargason, Marina Santiago, Juergen Hahn, Rosa Krajmalnik-Brown
mSphere Oct 2020, 5 (5) e00314-20; DOI: 10.1128/mSphere.00314-20
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KEYWORDS

autism spectrum disorder (ASD)
clinical trial
fecal microbiota transplant (FMT)
gut bacteria
metabolites
microbiome
microbiota transplant therapy (MTT)

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