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Editor's Pick Research Article | Therapeutics and Prevention

Identification of Simplified Microbial Communities That Inhibit Clostridioides difficile Infection through Dilution/Extinction

Jennifer M. Auchtung, Eva C. Preisner, James Collins, Armando I. Lerma, Robert A. Britton
Vincent B. Young, Editor
Jennifer M. Auchtung
aAlkek Center for Metagenomics and Microbiome Research, Baylor College of Medicine, Houston, Texas, USA
bDepartment of Molecular Virology and Microbiology, Baylor College of Medicine, Houston, Texas, USA
cNebraska Foods for Health Center, University of Nebraska—Lincoln, Lincoln, Nebraska, USA
dDepartment of Food Science and Technology, University of Nebraska—Lincoln, Lincoln, Nebraska, USA
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  • ORCID record for Jennifer M. Auchtung
Eva C. Preisner
aAlkek Center for Metagenomics and Microbiome Research, Baylor College of Medicine, Houston, Texas, USA
bDepartment of Molecular Virology and Microbiology, Baylor College of Medicine, Houston, Texas, USA
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James Collins
aAlkek Center for Metagenomics and Microbiome Research, Baylor College of Medicine, Houston, Texas, USA
bDepartment of Molecular Virology and Microbiology, Baylor College of Medicine, Houston, Texas, USA
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Armando I. Lerma
aAlkek Center for Metagenomics and Microbiome Research, Baylor College of Medicine, Houston, Texas, USA
bDepartment of Molecular Virology and Microbiology, Baylor College of Medicine, Houston, Texas, USA
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Robert A. Britton
aAlkek Center for Metagenomics and Microbiome Research, Baylor College of Medicine, Houston, Texas, USA
bDepartment of Molecular Virology and Microbiology, Baylor College of Medicine, Houston, Texas, USA
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Vincent B. Young
University of Michigan—Ann Arbor
Roles: Editor
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DOI: 10.1128/mSphere.00387-20
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Article Information

DOI 
https://doi.org/10.1128/mSphere.00387-20
PubMed 
32727857

Published By 
American Society for Microbiology Journals
History 
  • Received April 27, 2020
  • Accepted July 1, 2020
  • Published online July 29, 2020.

Copyright & Usage 
Copyright © 2020 Auchtung et al. This is an open-access article distributed under the terms of the Creative Commons Attribution 4.0 International license.
Editors and / or Reviewers 
  • Vincent B. Young, Editor, University of Michigan—Ann Arbor

Author Information

  1. Jennifer M. Auchtunga,b,c,d,
  2. Eva C. Preisnera,b,
  3. James Collinsa,b*,
  4. Armando I. Lermaa,b* and
  5. Robert A. Brittona,b
  1. aAlkek Center for Metagenomics and Microbiome Research, Baylor College of Medicine, Houston, Texas, USA
  2. bDepartment of Molecular Virology and Microbiology, Baylor College of Medicine, Houston, Texas, USA
  3. cNebraska Foods for Health Center, University of Nebraska—Lincoln, Lincoln, Nebraska, USA
  4. dDepartment of Food Science and Technology, University of Nebraska—Lincoln, Lincoln, Nebraska, USA
  • Address correspondence to Robert A. Britton, robert.britton{at}bcm.edu.
  • ↵* Present address: James Collins, Department of Microbiology & Immunology, University of Louisville School of Medicine, Louisville, Kentucky, USA; Armando I. Lerma, Department of Food Science and Technology, University of Nebraska—Lincoln, Lincoln, Nebraska, USA.

  • For a commentary on this article, see https://doi.org/10.1128/mSphere.00701-20.

  • Citation Auchtung JM, Preisner EC, Collins J, Lerma AI, Britton RA. 2020. Identification of simplified microbial communities that inhibit Clostridioides difficile infection through dilution/extinction. mSphere 5:e00387-20. https://doi.org/10.1128/mSphere.00387-20.

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Identification of Simplified Microbial Communities That Inhibit Clostridioides difficile Infection through Dilution/Extinction
Jennifer M. Auchtung, Eva C. Preisner, James Collins, Armando I. Lerma, Robert A. Britton
mSphere Jul 2020, 5 (4) e00387-20; DOI: 10.1128/mSphere.00387-20

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Identification of Simplified Microbial Communities That Inhibit Clostridioides difficile Infection through Dilution/Extinction
Jennifer M. Auchtung, Eva C. Preisner, James Collins, Armando I. Lerma, Robert A. Britton
mSphere Jul 2020, 5 (4) e00387-20; DOI: 10.1128/mSphere.00387-20
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KEYWORDS

Clostridioides difficile
FMT
colonization resistance
microbiome
simplified communities

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