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Editor's Pick Research Article | Host-Microbe Biology

Intranasal Inoculation of Cryptococcus neoformans in Mice Produces Nasal Infection with Rapid Brain Dissemination

Carolina Coelho, Emma Camacho, Antonio Salas, Alexandre Alanio, Arturo Casadevall
Aaron P. Mitchell, Editor
Carolina Coelho
aW. Harry Feinstone Department of Molecular Microbiology and Immunology, Johns Hopkins University Bloomberg School of Public Health, Baltimore, Maryland, USA
bMedical Research Council Centre for Medical Mycology, Institute of Medical Sciences, University of Aberdeen, Aberdeen, United Kingdom
cDepartment of Biosciences, College of Life and Environmental Sciences, University of Exeter, Exeter, United Kingdom
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  • ORCID record for Carolina Coelho
Emma Camacho
aW. Harry Feinstone Department of Molecular Microbiology and Immunology, Johns Hopkins University Bloomberg School of Public Health, Baltimore, Maryland, USA
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Antonio Salas
dJohns Hopkins School of Medicine, Baltimore, Maryland, USA
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Alexandre Alanio
eInstitut Pasteur, Molecular Mycology Unit, CNRS UMR2000, Université Paris Diderot, Sorbonne Paris Cité, Paris, France
fLaboratoire de Parasitologie-Mycologie, Hôpital Saint-Louis, Groupe Hospitalier Lariboisière, Saint-Louis, Fernand Widal, Assistance Publique-Hôpitaux de Paris (AP-HP), Paris, France
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Arturo Casadevall
aW. Harry Feinstone Department of Molecular Microbiology and Immunology, Johns Hopkins University Bloomberg School of Public Health, Baltimore, Maryland, USA
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Aaron P. Mitchell
Carnegie Mellon University
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DOI: 10.1128/mSphere.00483-19
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Article Information

DOI 
https://doi.org/10.1128/mSphere.00483-19
PubMed 
31391283

Published By 
American Society for Microbiology Journals
History 
  • Received July 7, 2019
  • Accepted July 22, 2019
  • Published online August 7, 2019.

Copyright & Usage 
Copyright © 2019 Coelho et al. This is an open-access article distributed under the terms of the Creative Commons Attribution 4.0 International license.
Editors and / or Reviewers 
  • Aaron P. Mitchell, Editor, Carnegie Mellon University

Author Information

  1. Carolina Coelhoa,b,c,
  2. Emma Camachoa,
  3. Antonio Salasd,
  4. Alexandre Alanioe,f and
  5. Arturo Casadevalla
  1. aW. Harry Feinstone Department of Molecular Microbiology and Immunology, Johns Hopkins University Bloomberg School of Public Health, Baltimore, Maryland, USA
  2. bMedical Research Council Centre for Medical Mycology, Institute of Medical Sciences, University of Aberdeen, Aberdeen, United Kingdom
  3. cDepartment of Biosciences, College of Life and Environmental Sciences, University of Exeter, Exeter, United Kingdom
  4. dJohns Hopkins School of Medicine, Baltimore, Maryland, USA
  5. eInstitut Pasteur, Molecular Mycology Unit, CNRS UMR2000, Université Paris Diderot, Sorbonne Paris Cité, Paris, France
  6. fLaboratoire de Parasitologie-Mycologie, Hôpital Saint-Louis, Groupe Hospitalier Lariboisière, Saint-Louis, Fernand Widal, Assistance Publique-Hôpitaux de Paris (AP-HP), Paris, France
  • Address correspondence to Carolina Coelho, c.coelho{at}exeter.ac.uk, or Arturo Casadevall, arturo.casadevall{at}jhu.edu.
  • Citation Coelho C, Camacho E, Salas A, Alanio A, Casadevall A. 2019. Intranasal inoculation of Cryptococcus neoformans in mice produces nasal infection with rapid brain dissemination. mSphere 4:e00483-19. https://doi.org/10.1128/mSphere.00483-19.

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Intranasal Inoculation of Cryptococcus neoformans in Mice Produces Nasal Infection with Rapid Brain Dissemination
Carolina Coelho, Emma Camacho, Antonio Salas, Alexandre Alanio, Arturo Casadevall
mSphere Aug 2019, 4 (4) e00483-19; DOI: 10.1128/mSphere.00483-19

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Intranasal Inoculation of Cryptococcus neoformans in Mice Produces Nasal Infection with Rapid Brain Dissemination
Carolina Coelho, Emma Camacho, Antonio Salas, Alexandre Alanio, Arturo Casadevall
mSphere Aug 2019, 4 (4) e00483-19; DOI: 10.1128/mSphere.00483-19
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KEYWORDS

Cryptococcus
Cryptococcus gattii
Cryptococcus neoformans
brain
infection
nose

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