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Research Article | Host-Microbe Biology

The Protective Role of Bacteroides fragilis in a Murine Model of Colitis-Associated Colorectal Cancer

Yun Kyung Lee, Parpi Mehrabian, Silva Boyajian, Wei-Li Wu, Jane Selicha, Steven Vonderfecht, Sarkis K. Mazmanian
Julia Oh, Editor
Yun Kyung Lee
aDivision of Biology & Biological Engineering, California Institute of Technology, Pasadena, California, USA
bSoonchunhyang Institute of Medi-Bio Science, Soonchunhyang University, Cheonan, Republic of Korea
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Parpi Mehrabian
aDivision of Biology & Biological Engineering, California Institute of Technology, Pasadena, California, USA
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Silva Boyajian
aDivision of Biology & Biological Engineering, California Institute of Technology, Pasadena, California, USA
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Wei-Li Wu
aDivision of Biology & Biological Engineering, California Institute of Technology, Pasadena, California, USA
dDepartment of Physiology, College of Medicine, National Cheng Kung University, Tainan, Taiwan
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Jane Selicha
aDivision of Biology & Biological Engineering, California Institute of Technology, Pasadena, California, USA
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Steven Vonderfecht
cCenter for Comparative Medicine, Beckman Research Institute, City of Hope, Duarte, California, USA
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Sarkis K. Mazmanian
aDivision of Biology & Biological Engineering, California Institute of Technology, Pasadena, California, USA
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Julia Oh
The Jackson Laboratory for Genomic Medicine
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DOI: 10.1128/mSphere.00587-18
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Article Information

DOI 
https://doi.org/10.1128/mSphere.00587-18
PubMed 
30429227

Published By 
American Society for Microbiology Journals
History 
  • Received October 25, 2018
  • Accepted October 26, 2018
  • Published online November 14, 2018.

Copyright & Usage 
Copyright © 2018 Lee et al. This is an open-access article distributed under the terms of the Creative Commons Attribution 4.0 International license.
Editors and / or Reviewers 
  • Julia Oh, Editor, The Jackson Laboratory for Genomic Medicine

Author Information

  1. Yun Kyung Leea,b,
  2. Parpi Mehrabiana,
  3. Silva Boyajiana,
  4. Wei-Li Wua,d,
  5. Jane Selichaa,
  6. Steven Vonderfechtc and
  7. Sarkis K. Mazmaniana
  1. aDivision of Biology & Biological Engineering, California Institute of Technology, Pasadena, California, USA
  2. bSoonchunhyang Institute of Medi-Bio Science, Soonchunhyang University, Cheonan, Republic of Korea
  3. cCenter for Comparative Medicine, Beckman Research Institute, City of Hope, Duarte, California, USA
  4. dDepartment of Physiology, College of Medicine, National Cheng Kung University, Tainan, Taiwan
  • Address correspondence to Yun Kyung Lee, yunklee{at}sch.ac.kr.
  • Citation Lee YK, Mehrabian P, Boyajian S, Wu W-L, Selicha J, Vonderfecht S, Mazmanian SK. 2018. The protective role of Bacteroides fragilis in a murine model of colitis-associated colorectal cancer. mSphere 3:e00587-18. https://doi.org/10.1128/mSphere.00587-18.

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The Protective Role of Bacteroides fragilis in a Murine Model of Colitis-Associated Colorectal Cancer
Yun Kyung Lee, Parpi Mehrabian, Silva Boyajian, Wei-Li Wu, Jane Selicha, Steven Vonderfecht, Sarkis K. Mazmanian
mSphere Nov 2018, 3 (6) e00587-18; DOI: 10.1128/mSphere.00587-18

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The Protective Role of Bacteroides fragilis in a Murine Model of Colitis-Associated Colorectal Cancer
Yun Kyung Lee, Parpi Mehrabian, Silva Boyajian, Wei-Li Wu, Jane Selicha, Steven Vonderfecht, Sarkis K. Mazmanian
mSphere Nov 2018, 3 (6) e00587-18; DOI: 10.1128/mSphere.00587-18
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KEYWORDS

Bacteroides fragilis
Toll-like receptor 2
colitis-associated colorectal cancer
inflammation
polysaccharide A

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