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Research Article | Clinical Science and Epidemiology

Development and Validation of 13-plex Luminex-Based Assay for Measuring Human Serum Antibodies to Streptococcus pneumoniae Capsular Polysaccharides

Danka Pavliakova, Peter C. Giardina, Soraya Moghazeh, Shite Sebastian, Maya Koster, Viliam Pavliak, Andrew McKeen, Roger French, Kathrin U. Jansen, Michael Pride
Patricia P. Wilkins, Editor
Danka Pavliakova
aVaccine Research and Development and Early Clinical Development Biostatistics, Pfizer Inc., Pearl River, New York, USA
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Peter C. Giardina
aVaccine Research and Development and Early Clinical Development Biostatistics, Pfizer Inc., Pearl River, New York, USA
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Soraya Moghazeh
aVaccine Research and Development and Early Clinical Development Biostatistics, Pfizer Inc., Pearl River, New York, USA
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Shite Sebastian
bAffinivax, Cambridge, Massachusetts, USA
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Maya Koster
aVaccine Research and Development and Early Clinical Development Biostatistics, Pfizer Inc., Pearl River, New York, USA
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Viliam Pavliak
aVaccine Research and Development and Early Clinical Development Biostatistics, Pfizer Inc., Pearl River, New York, USA
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Andrew McKeen
cBiotechnology Clinical Development Statistics, Pfizer Inc., Pearl River, New York, USA
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Roger French
cBiotechnology Clinical Development Statistics, Pfizer Inc., Pearl River, New York, USA
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Kathrin U. Jansen
aVaccine Research and Development and Early Clinical Development Biostatistics, Pfizer Inc., Pearl River, New York, USA
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Michael Pride
aVaccine Research and Development and Early Clinical Development Biostatistics, Pfizer Inc., Pearl River, New York, USA
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Patricia P. Wilkins
Parasitology Services
Roles: Editor
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DOI: 10.1128/mSphere.00128-18
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Article Information

DOI 
https://doi.org/10.1128/mSphere.00128-18
PubMed 
30089645

Published By 
American Society for Microbiology Journals
History 
  • Received March 12, 2018
  • Accepted June 9, 2018
  • Published online August 8, 2018.

Copyright & Usage 
Copyright © 2018 Pavliakova et al. This is an open-access article distributed under the terms of the Creative Commons Attribution 4.0 International license.
Editors and / or Reviewers 
  • Patricia P. Wilkins, Editor, Parasitology Services

Author Information

  1. Danka Pavliakovaa,
  2. Peter C. Giardinaa,
  3. Soraya Moghazeha,
  4. Shite Sebastianb,
  5. Maya Kostera,
  6. Viliam Pavliaka*,
  7. Andrew McKeenc,
  8. Roger Frenchc,
  9. Kathrin U. Jansena and
  10. Michael Pridea
  1. aVaccine Research and Development and Early Clinical Development Biostatistics, Pfizer Inc., Pearl River, New York, USA
  2. bAffinivax, Cambridge, Massachusetts, USA
  3. cBiotechnology Clinical Development Statistics, Pfizer Inc., Pearl River, New York, USA
  • Address correspondence to Danka Pavliakova, danka.pavliakova{at}pfizer.com.
  • ↵* Present address: Viliam Pavliak, International Vaccine Institute, Seoul, South Korea.

  • Citation Pavliakova D, Giardina PC, Moghazeh S, Sebastian S, Koster M, Pavliak V, McKeen A, French R, Jansen KU, Pride M. 2018. Development and validation of 13-plex Luminex-based assay for measuring human serum antibodies to Streptococcus pneumoniae capsular polysaccharides. mSphere 3:e00128-18. https://doi.org/10.1128/mSphere.00128-18.

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Development and Validation of 13-plex Luminex-Based Assay for Measuring Human Serum Antibodies to Streptococcus pneumoniae Capsular Polysaccharides
Danka Pavliakova, Peter C. Giardina, Soraya Moghazeh, Shite Sebastian, Maya Koster, Viliam Pavliak, Andrew McKeen, Roger French, Kathrin U. Jansen, Michael Pride
mSphere Aug 2018, 3 (4) e00128-18; DOI: 10.1128/mSphere.00128-18

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Development and Validation of 13-plex Luminex-Based Assay for Measuring Human Serum Antibodies to Streptococcus pneumoniae Capsular Polysaccharides
Danka Pavliakova, Peter C. Giardina, Soraya Moghazeh, Shite Sebastian, Maya Koster, Viliam Pavliak, Andrew McKeen, Roger French, Kathrin U. Jansen, Michael Pride
mSphere Aug 2018, 3 (4) e00128-18; DOI: 10.1128/mSphere.00128-18
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KEYWORDS

Luminex
development
multiplex
pneumococcal
validation

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