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Editor's Pick Commentary | Therapeutics and Prevention

A Critical Analysis of the Scientific and Commercial Rationales for the De Novo Synthesis of Horsepox Virus

Gregory D. Koblentz
Gregory D. Koblentz
aSchar School of Policy and Government, George Mason University, Arlington, Virginia, USA
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DOI: 10.1128/mSphere.00040-18
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Article Information

DOI 
https://doi.org/10.1128/mSphere.00040-18
PubMed 
29569633

Published By 
American Society for Microbiology Journals
History 
  • Published online March 7, 2018.

Copyright & Usage 
Copyright © 2018 Koblentz. This is an open-access article distributed under the terms of the Creative Commons Attribution 4.0 International license.

Author Information

  1. Gregory D. Koblentza
  1. aSchar School of Policy and Government, George Mason University, Arlington, Virginia, USA
  • Address correspondence to gkoblent{at}gmu.edu.
  • Citation Koblentz GD. 2018. A critical analysis of the scientific and commercial rationales for the de novo synthesis of horsepox virus. mSphere 3:e00040-18. https://doi.org/10.1128/mSphere.00040-18.

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A Critical Analysis of the Scientific and Commercial Rationales for the De Novo Synthesis of Horsepox Virus
Gregory D. Koblentz
mSphere Mar 2018, 3 (2) e00040-18; DOI: 10.1128/mSphere.00040-18

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A Critical Analysis of the Scientific and Commercial Rationales for the De Novo Synthesis of Horsepox Virus
Gregory D. Koblentz
mSphere Mar 2018, 3 (2) e00040-18; DOI: 10.1128/mSphere.00040-18
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  • Top
  • Article
    • ABSTRACT
    • COMMENTARY
    • EVALUATING THE SCIENTIFIC AND COMMERCIAL RATIONALES FOR SYNTHESIZING HORSEPOX VIRUS
    • WEAK SCIENTIFIC BASIS FOR HORSEPOX VIRUS STRAIN MNR-76 AS ANCESTRAL STRAIN FOR VACCINIA
    • WEAK SCIENTIFIC BASIS THAT HORSEPOX VIRUS WOULD BE SAFER ALTERNATIVE FOR HUMAN VACCINE USE
    • NO DEMONSTRATED NEED FOR A SAFER SMALLPOX VACCINE
    • NO DEMAND FOR A NEW SMALLPOX VACCINE
    • CONCLUSION
    • ACKNOWLEDGMENTS
    • FOOTNOTES
    • REFERENCES
  • Info & Metrics
  • PDF

KEYWORDS

DNA synthesis
biosecurity
dual use research
horsepox
smallpox
synthetic biology
vaccines

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