TABLE 1 

Surface protein markers evaluated in this study

Marker(s)FunctionReference(s)
CD36M2 marker, uptake of fatty acids and oxidized low-density lipoprotein, relevant to mycobacterial pathogenesis36, 37
CD64M1 marker (Fc-gamma receptor 1), binding to monomeric IgG-type antibodies, macrophage activation38
CD80, CD86M1 markers, costimulatory signals necessary for T cell activation and survival39
CD163M2 marker, macrophage iron uptake, relevant to mycobacterial pathogenesis40
CD206Pattern recognition receptor (mannose receptor), M. tuberculosis uptake41, 42
LDLRCell surface receptor, cholesterol homeostasis43
TLR2, TLR4Pattern recognition receptors, interaction with M. tuberculosis lipoproteins and lipopolysaccharides13, 41