TABLE 1 

Description of strain isolation, sequencing and assembly, and drug resistance profiles for eye-associated S. pneumoniae strains

ParameterResult for strain:
E709K2521K2527K2557B1598B1599
Isolation date
(mo/day/yr)
5/13/131/28/132/21/136/19/1310/19/1211/3/12
Isolation siteUPMCUPMCUPMCUPMCUPMCUPMC
Serotypea23A15B19A17FNENE
MLST3383280320235523152315
Accession no.
    GenBankJBOR00000000JBOS00000000JBOT00000000JBOU00000000JBOV00000000JBOW00000000
    BioProjectPRJNA235160PRJNA235267PRJNA235268PRJNA235269PRJNA235270PRJNA235271
    BioSampleSAMN02691894SAMN02691895SAMN02691896SAMN02691897SAMN02691898SAMN02691899
CG (%)39.639.639.839.839.639.6
No. of contigs37322911115838
Read coverage (×)55.2273.7163.1330.3952.0749.71
Sequencing
platform
SMRTSMRTSMRTSMRTSMRTSMRT
Estimated genome
size (bp)
2,155,1212,184,8122,180,2902,051,6812,902,5652,422,872
ResistanceGentamicin,
amikacin
Tobramycin,
polymyxin B
Gentamicin,
tobramycin,
polymyxin B
Gentamicin,
polymyxin B,
tobramycin,
sulfonamide,
ciprofloxacin,b
ofloxacinb
Gentamicin,
trimethoprim,
polymyxin B,
tobramycin
Gentamicin,
trimethoprim,
polymyxin B,
tobramycin
  • a Serotypes were determined based on genome sequence. NE, nonencapsulated.

  • b Intermediate resistance.